Pediatric Low-grade Gliomas Clinical Trial
Official title:
Developing Fast Pediatric Imaging
This research study is evaluating the investigational software for magnetic resonance imaging (MRI) systems and techniques to process magnetic resonance (MR) images
Status | Recruiting |
Enrollment | 300 |
Est. completion date | March 1, 2025 |
Est. primary completion date | September 1, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 0 Years and older |
Eligibility | Inclusion Criteria: - Infants, children and adults who have been diagnosed with Low Grade Glioma - Healthy volunteers - Children from age 0 to adults with no upper age limit or; - Diagnosed with LGG and being treated at DFCI; Exclusion Criteria: - Electrical implants such as cardiac pacemakers or perfusion pumps; - Ferromagnetic implants such as aneurysm clips, surgical clips, prosthesis, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants; - Ferromagnetic objects such as jewelry or metal clips; - Women of childbearing age who are seeking to become pregnant, who are breastfeeding, or who suspect they may be pregnant; - Pre-existing medical conditions including a likelihood of developing seizures or claustrophobic reactions; - Any greater than normal potential for cardiac arrest |
Country | Name | City | State |
---|---|---|---|
United States | Boston Children Hospital | Boston | Massachusetts |
United States | Dana Farber Cancer Institute | Boston | Massachusetts |
United States | Massachusetts General Hospital | Boston | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
Boston Children's Hospital | Dana-Farber Cancer Institute, National Institute for Biomedical Imaging and Bioengineering (NIBIB) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Wave-CAIPI validation | The outcome measure for this project will be that the rapid scan from Wave-CAIPI can provide equivalent diagnostic quality to that of standard clinical acquisitions which is performed at much slower speed. This will be assess using visual qualitative assessment by experienced radiologists on the project. | 2 years |