Pediatric Critical Illness Clinical Trial
Official title:
Functional Recovery in Critically Ill Children - a Longitudinal Multicentre, Mixed-Methods Study
When children suffer from a critical-illness, the investigators focus on resuscitating and
saving lives. Once these children leave the pediatric intensive care unit, very little is
known about what happens to them - how long it takes for them to recover, how families cope,
and what factors that impede their recovery. The specific objective of this research project
is to evaluate how children and their families recover after a critical illness.
Research Hypotheses: Following a critical illness in children, 1) the rate and degree of
health and functional recovery is influenced by the following factors: age, pre-admission
co-morbid status, critical illness severity, discharge functional status, and time to
initiating acute rehabilitation; 2) functional recovery is influenced by caregiver burden and
health-related quality-of-life (HRQoL).
The Specific Objective of this study is to evaluate the trajectory of health and functional
outcomes in children following a critical illness, define poor functional recovery, and
evaluate predictors of poor recovery.
The Research Questions for this study are: 1) What are the health and functional outcomes in
children affected by a critical illness, at 3 and 6 months following Pediatric Intensive Care
Unit (PICU) discharge? 2) What defines poor functional recovery? 3) What are predictors of
poor functional recovery in critically ill children? 4) What are the most important and
relevant outcomes in critically ill children, from the patient and caregiver's point of view?
Study Design: Prospective Observational Mixed Methods Longitudinal Cohort Study Study
Setting: Two Academic Pediatric Centres in Canada - McMaster Children's Hospital and London
Health Sciences Centre.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05733975 -
Decision Making Support for Parents and Caregivers
|
N/A | |
| Completed |
NCT03223038 -
Pediatric International Nutrition Study 2018
|