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Pediatric Cancer Patients clinical trials

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NCT ID: NCT04873284 Not yet recruiting - Clinical trials for Chemotherapy Induced Nausea and Vomiting

Comparative Study of Fosaprepitant and Aprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting in Pediatric Caner Patients

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

Children aged 2-12 years scheduled to receive moderately or highly emetogenic chemotherapy were randomly assigned to arm-A (fosaprepitant) or arm-B (aprepitant). Children recruited to arm-A received intravenous granisetron plus dexamethasone followed by fosaprepitant infusion. Children recruited to arm-B received the same drugs as those given to children in arm-A, except that fosaprepitant was substituted with aprepitant. Granisetron and dexamethasone were given continuously until 48 hours after completion of chemotherapy. The primary end point of the study was to determine the proportion of patients who achieved a CR, defined as no vomiting, no retching, and no use of rescue medication, the proportion of patients who achieved a CR during the acute phase (0-24 hours) after administration of the last dose of chemotherapy. Secondary end points were the proportion of patients who achieved a CR during the 24-120 hours (delayed phase) and overall after administration of the last dose of chemotherapy.

NCT ID: NCT04831359 Recruiting - Clinical trials for Pediatric Cancer Patients

Tissue Doppler Assessment of Right Ventricle Function in Pediatrics Underwent Chemotherapy

Start date: February 20, 2021
Phase:
Study type: Observational

Tissue Doppler assessment of right ventricular function in newly diagnosed pediatric cancer patients underwent chemotherapy in South Egypt Cancer Institute.

NCT ID: NCT02836041 Completed - Clinical trials for Pediatric Cancer Patients

Sleep in Hospitalized Children at MSKCC

Start date: July 7, 2016
Phase:
Study type: Observational

The investigators want to better understand how children sleep at night at MSKCC, so that the investigators can learn how to improve the sleeping environment.

NCT ID: NCT02644993 Recruiting - Clinical trials for Pediatric Cancer Patients

Registry for Analysis of Quality of Life, Normal Organ Toxicity and Survival of Pediatric Patients Treated With Proton Therapy

Start date: November 2015
Phase: N/A
Study type: Interventional

The study aim of this study is to evaluate the effect of proton therapy on quality of life and long-term normal tissue toxicities of the pediatric cancer patients. Based on these results, the predictive model of long-term normal tissue toxicities, survival, and quality of life could be recognized. Risk-adapted treatment strategy based on the predictive model in pediatric cancer patients could be established.