Pediatric ALL Clinical Trial
Official title:
The Effect of Low Dose Nalbuphine or Ketamine in the Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children Undergoing Tonsillectomy With or Without Adenoidectomy
The effect of low dose nalbuphine or ketamine in the prevention of emergence agitation after sevoflurane anesthesia in children undergoing tonsillectomy with or without adenoidectomy. This randomized double-blind study was carried out at, Ain shams University Hospitals, from March 2021 to June 2021 on 90 patients after approval of the ethical committee.
Emergence agitation (EA) in children is increased after sevoflurane anesthesia. Nalbuphine and midazolam have been used for prophylactic treatment with controversial results. Patients and Methods:Totally, 90 children between 4 and 10 years of age and of American Society of Anesthesiologists I-II undergoing adenotonsillectomy under sevoflurane-based anesthesia were enrolled in the study. Children were randomly allocated to one of the three groups: Group N received nalbuphine 0.1 mg/kg, Group K received ketamine 0.25 mg /kg and Group S received the equivalent volume saline. The study medications was given after discontinuation of sevoflurane by the end of surgery. In the post anesthesia care unit emergence agitation was assessed with emergence agitation scale upon admission (T0), after 5 min (T5), 10 min (T10), 15 min (T15), 20 min (T20), 25 min (T25) and 30 min (T30). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT05818644 -
Hepatic Artery Stenosis and Thrombosis After Liver Transplantation in Children
|
||
| Not yet recruiting |
NCT06018324 -
CloudCare in the Treatment of Type 1 Diabetes in Pediatrics
|
||
| Not yet recruiting |
NCT04523623 -
Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries
|
N/A | |
| Completed |
NCT02930850 -
Spot-Check Noninvasive Hemoglobin (SpHb) Clinical Validation
|
N/A | |
| Completed |
NCT03385681 -
Pediatric Pain Management - an Intervention Study
|
N/A | |
| Completed |
NCT00229671 -
Medication Errors and Adverse Drug Events (ADEs) in Ambulatory Pediatrics
|
N/A | |
| Completed |
NCT04465370 -
Pediatric Cardiac Output Monitoring Observational Study
|
||
| Recruiting |
NCT04100070 -
Intensive Versus Standard One Year Monitoring on Glycaemic Control After Initiating CSII in Children With DT1. DEEP Study
|
N/A | |
| Not yet recruiting |
NCT06035757 -
The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery
|
Phase 4 | |
| Completed |
NCT03369847 -
Inhaled Steroids for Pediatric Asthma at Pediatric Emergency Medicine Discharge
|
Phase 4 | |
| Completed |
NCT05474170 -
Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
|
N/A | |
| Recruiting |
NCT05230004 -
Innovative Prosthetic Systems for Pediatric Limb Loss to Accommodate Growth
|
N/A | |
| Completed |
NCT05731401 -
Expressed Beliefs About the Cause of Pain in a Paediatric Population
|
||
| Completed |
NCT06376188 -
Improving Breaking Bad News in Pediatrics by Simulated Communication
|
N/A | |
| Completed |
NCT05818215 -
Impact of the Qatar 2022 FIFA World Cup on PED Use and Misuse Patterns
|
||
| Completed |
NCT04589910 -
Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.
|
N/A | |
| Recruiting |
NCT04252508 -
Impact of a Double-reading Animated Film (Child, Parents) in Preoperative on the Anxiety of Children Upon Arrival at the Operating Room
|
N/A | |
| Completed |
NCT04655378 -
Validation of the IgA1 Detection Method With Gradient Glycosylation by Mass Spectrometry as a Potential Marker of Renal Involvement in Pediatric Rheumatoid Purpura
|
||
| Completed |
NCT04610918 -
Comparing Body Composition Assessment Methods
|
||
| Completed |
NCT03964259 -
Reduced IV Fluids to Improve Clearance of HDMTX in Children w/Lymphoma or Acute Lymphoblastic Leukemia
|
Phase 1 |