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Oral Peanut Immunotherapy for Peanut Allergic Patients — PnOIT  

Peanut Hypersensitivity Clinical Trial

Official title:
Pilot Study: Oral Peanut Immunotherapy for Peanut Allergic Patients

Clinical Trial Summary

This is a study to determine if peanut oral immunotherapy (OIT) would desensitize or tolerize peanut allergic patients to peanuts in order prevent peanut allergic reactions.

Clinical Trial Description

The goal of this proposal is to develop peanut OIT for patients with peanut allergic reactions. This approach is designed to utilize our extensive knowledge of the allergens involved in peanut hypersensitivity to devise an immunotherapeutic approach that would lower the risk of anaphylactic reactions and would down regulate peanut-specific T cells in peanut-allergic patients. Previous attempts to utilize peanut-specific immunotherapy (IT) have been unsuccessful primarily because of the side effects of therapy. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01891136
Study type Interventional
Source University of North Carolina, Chapel Hill
Contact
Status Completed
Phase Phase 0
Start date April 2004
Completion date December 2014
View Details
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