Pinpoint Trial: Prebiotics IN Peanut Oral ImmunoTherapy

Status Recruiting

Clinical Trial Summary

The purpose of this research is to gather information on the safety and efficacy of using a prebiotic as an adjunctive therapy to peanut oral immunotherapy. The prebiotic is not an FDA approved drug or medication rather a fiber found at local grocery stores.

Clinical Trial Description

By doing this study, we hope to learn if using a dietary fiber called a "prebiotic" helps increase the number of children who can tolerate eating 1043mg of peanut protein (or about 3-4 peanuts) after going through oral immunotherapy (OIT) to peanut. We are also trying to determine if this fiber will reduce the side effects of OIT and if so, we would like to find out if the reason it is working is by changing the bacteria in the gut. Participation in this research will last about five years. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05138757
Study type	Interventional
Source	University of Chicago
Contact	Christina E Ciaccio, MD
Phone	773-834-4010
Email	cciaccio@bsd.uchicago.edu
Status	Recruiting
Phase	Phase 1/Phase 2
Start date	November 30, 2021
Completion date	December 30, 2025

View Details

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