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Study of Tolerance to Oral Peanut — STOP  

Peanut Allergy Clinical Trial

Official title:
Efficacy and Safety of High-dose Peanut Oral Immunotherapy With Factors Predicting Outcome

Clinical Trial Summary

Open pilot study of peanut oral immunotherapy in 22 children with peanut allergy

Clinical Trial Description

Background Peanut allergy is severe and rarely resolves.

Objective To test the efficacy and safety of a new oral immunotherapy protocol for peanut allergy.

Method 22 peanut-allergic children will undergo oral challenge. Oral immunotherapy will be administered by gradual updosing with 2-weekly increments (8-38w) to 800mg protein (5 peanuts/day) followed by 30-weeks maintenance. Oral challenge will be repeated after 6 and 30 weeks maintenance. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01259804
Study type Interventional
Source Cambridge University Hospitals NHS Foundation Trust
Contact
Status Completed
Phase Phase 1
Start date January 2008
Completion date January 2012
View Details
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