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Peanut Allergy clinical trials

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NCT ID: NCT03352726 Completed - Peanut Allergy Clinical Trials

A Study to Assess the Biological Potency of Peanut Allergen Extract in Adolescent and Adult Peanut Allergic Subjects

V712-103
Start date: November 24, 2017
Phase: Phase 1
Study type: Interventional

The study aims to assess the biological potency of the In-House Reference Preparation (IHRP) of peanut allergens extract by a quantitative Skin Prick Test (SPT) method in peanut-allergic subjects.

NCT ID: NCT03337542 Completed - Peanut Allergy Clinical Trials

AR101 Real-World Open-Label Extension Study

Start date: October 18, 2017
Phase: Phase 3
Study type: Interventional

This study is enrolling participants by invitation only. This is an open-label, safety extension study for subjects who participated in the ARC007 study.

NCT ID: NCT03292484 Completed - Peanut Allergy Clinical Trials

Longer-term Study of AR101 in Subjects Who Participated in a Prior AR101 Study (ARC008)

Start date: October 11, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess AR101's safety, tolerability and efficacy over an extended dosing period.

NCT ID: NCT03251508 Completed - Peanut Allergy Clinical Trials

Salvage Peanut Oral Immunotherapy Study

SOIT
Start date: January 3, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this trial is to study the safety of rescue peanut oral immunotherapy followed by the introduction of dietary peanut for patients with peanut allergy who have lost desensitization during a peanut immunotherapy trial.

NCT ID: NCT03201003 Completed - Peanut Allergy Clinical Trials

ARTEMIS Peanut Allergy In Children

ARTEMIS
Start date: June 12, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the efficacy and safety of AR101 through oral immunotherapy (OIT) in peanut-allergic children.

NCT ID: NCT03126227 Completed - Peanut Allergy Clinical Trials

Real-World AR101 Market-Supporting Experience Study in Peanut-Allergic Children (RAMSES)

RAMSES
Start date: May 8, 2017
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled safety study of AR101 using the characterized oral desensitization immunotherapy (CODITâ„¢) regimen in peanut-allergic children.

NCT ID: NCT03070561 Completed - Pharmacokinetics Clinical Trials

Evaluating Peanut Immunotherapy Dissolving Film in Healthy Subjects

Start date: January 14, 2014
Phase: Early Phase 1
Study type: Interventional

Open label, cross-over, local pharmacokinetics study of a sublingual film with peanut extract in healthy adults and children

NCT ID: NCT03019328 Completed - Peanut Allergy Clinical Trials

Early Peanut Introduction: Translation to Clinical Practice

EPI
Start date: December 2016
Phase:
Study type: Observational

The recent finding that early introduction of peanut can prevent ~70-90% of peanut allergy is a major step towards prevention of food allergy. However, because that finding was from a clinical trial in a very select population, there are several major questions that must be answered in order to implement these findings into clinical practice without causing more harm than good. These questions include who, if anyone, should be screened prior to early introduction for peanut allergy, how this screening should be done, and what quantity of peanut ingestion is needed to prevent peanut allergy. The goal of this project is to answer these critical questions so that the potential of these recent findings can be realized. To that end, 400 infants at high-risk of peanut allergy will be enrolled. These infants will be given a peanut skin prick test, peanut food challenge and have blood drawn for measurement of peanut IgE, and then will be followed for assessment of peanut consumption and development of peanut allergy until 3 years of age.

NCT ID: NCT02993107 Completed - Peanut Allergy Clinical Trials

PALISADE Follow-on Study (ARC004)

Start date: December 29, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the safety, tolerability, and efficacy of AR101 through oral immunotherapy (OIT) in peanut-allergic children and adults who have completed the ARC003 study.

NCT ID: NCT02991885 Completed - Peanut Allergy Clinical Trials

HAL-MPE1 Safety and Tolerability Study

Start date: December 2016
Phase: Phase 1
Study type: Interventional

The aim of this study is to confirm safety and tolerability of incremental doses of HAL-MPE1 subcutaneous immunotherapy (SCIT) in peanut allergic adults, and subsequently assess the safety and tolerability in adolescents and children with peanut allergy.