Role of MSCT of Chest in Differentiation Between COPD Patients According to Their Smoking Status

Patient Participation Clinical Trial

Official title:

Role of Multislice Computed Tomography (MSCT) Chest in Differentiation Between Chronic Obstructive Pulmonary Disease(COPD) Patients According to Their Smoking Status

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05475977
• Other study ID #: Somaia Ahmad
• Status: Not yet recruiting
• Start date: August 2022
• Est. completion date: July 2023

Study information

• Verified date: August 2022
• Source: Assiut University
• Contact: Somaia Ahmad AbdAllah Ahmad, M.B.B.Ch
• Phone: 01024833938
• Email: somayaahmad64[@]gmail.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality all over the world. Smoking is considered as an important risk factor, but other risk factors are present. Around 30 % of patients with COPD are non-smokers.

Cessation of smoking in patients with COPD causes decreases the presence of micronodules and other criteria of CT chest.

In last few years, some researchers reported that cessation of smoking raise the apparent extent of emphysema. The cause is not obvious, but this paradoxical fall in lung density is thaught to be resulting from decrease in inflammation after smoking cessation.

CT chest criteria of COPD in active smokers, non-smokers and ex-smokers seem to be different.

So, comparison between CT chest Criteria of COPD in smokers, ex-smokers and non-smokers will be searched in this study to detect the role of multislice computed tomography (MSCT) chest in differentiation between COPD patients according to their smoking status.

Description:

Basic ethical principles of medical research; beneficence (do well), non-maleficence (do no harm), respect and distributive justice were implemented. The study will be carried out in accordance with the Declaration of Helsinki and the principles of good clinical practice.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 90
• Est. completion date: July 2023
• Est. primary completion date: April 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. All patients with chronic obstructive Pulmonary Disease.

2. Patients above 18 years.

Exclusion Criteria:

1. Patients with unclear smoking history.

2. Patients with active pneumonia.

3. Patients with acute COPD exacerbation.

Related Conditions & MeSH terms

• Patient Participation

Intervention

Diagnostic Test:
• MSCT chest
Multi slice Computed Tomography of the chest

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Somaia Ahmad AbdAllah Ahmad

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of participants with criteria of severe COPD	Criteria of severe COPD include emphysematous bullae, thick bronchial walls.	18 months