Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble

Status Completed

Clinical Trial Summary

This study is designed to test the hypothesis that ecopipam is able to reduce urges to gamble in patients diagnosed with Pathological Gambling.

Clinical Trial Description

The purpose of this study is to determine if ecopipam is able to stop urges to gamble in patients diagnosed with Pathological Gambling. Nerves communicate with each other by releasing chemicals called "neurotransmitters". One of these neurotransmitters in the brain is called "dopamine". After dopamine is released by the nerve it "talks" to other nerves by interacting with receptors that are unique to that neurotransmitter. Ecopipam is a drug that selectively blocks one family of dopamine receptors. Some scientists believe that the urge to gamble is related to having too much dopamine in the brain. By blocking the receptors that dopamine uses, ecopipam may be able to relieve the urge to gamble. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01215357
Study type	Interventional
Source	Emalex Biosciences Inc.
Contact
Status	Completed
Phase	Phase 2
Start date	October 2010
Completion date	August 2012

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02590211` - Poker, Skills and Associated Problems	N/A
Completed	`NCT02203786` - D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement	Phase 2
Completed	`NCT05051085` - Feasibility of the Internet-delivered Treatment "SpilleFri" for Patients With Pathological Gambling	N/A
Terminated	`NCT00245583` - Topiramate in the Treatment of Pathological Gambling	Phase 3
Completed	`NCT04842461` - Mental Health, Addictions and Biomarkers in High Athletes Performance
Not yet recruiting	`NCT03280966` - Effects of Intranasal Naloxone on Gambling Urges in Gambling Disorder	Phase 2
Active, not recruiting	`NCT01743092` - Testing Resources: Manual and Webinar Guided Treatment vs. Manual Guided Treatment	N/A
Active, not recruiting	`NCT01528982` - Susceptibility to Pathological Gambling	N/A
Terminated	`NCT00211822` - Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD)	N/A
Completed	`NCT01381250` - Effects of Internet-based Treatment of Pathological Gambling	N/A
Completed	`NCT05506384` - Treatment Study for Problematic Gaming and Gambling	N/A
Enrolling by invitation	`NCT03464838` - Effects of Transcranial Direct Current Stimulation (tDCS) in Gambling Disorder	N/A
Terminated	`NCT01560351` - Repeated Low-frequency Transcranial Magnetic Stimulation Reduces Cue-induced Craving: a Randomized, Prospective, Double-blind, Sham-controlled, Cross-over Study	N/A
Completed	`NCT00580567` - Impulsivity in Pathological Gambling	N/A
Completed	`NCT02240485` - Integrative Couple Treatment for Pathological Gambling	N/A
Withdrawn	`NCT01340274` - Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling	Phase 2
Recruiting	`NCT02491996` - The Efficacy of Therapy Focused on Desire-satisfaction for Disordered Gamblers	N/A
Recruiting	`NCT01154712` - Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for Cessation of Pathological Gambling	Phase 1
Completed	`NCT01843699` - Topiramate Trial for Pathological Gamblers	Phase 2
Completed	`NCT00927563` - Tolcapone Treatment of Pathological Gambling	Phase 2