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Clinical Trial Summary

The investigator's purpose is to study the population pharmacokinetics of paracatamol and ibuprofen in neonates with patent ductus arteriosus (PDA) and assess the feasibility of dosage individualization.


Clinical Trial Description

The investigator's purpose is to study the population pharmacokinetics of paracatamol and ibuprofen in neonates with patent ductus arteriosus (PDA) and assess the feasibility of dosage individualization. In this study, the investigator will detect drug concentration in plasma and other clinical test to construct population pharmacokinetic models. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04397913
Study type Observational
Source Shandong University
Contact Wei Zhao, Ph.D
Phone 053188383308
Email zhao4wei2@hotmail.com
Status Recruiting
Phase
Start date May 25, 2020
Completion date May 6, 2023

See also
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Completed NCT03277768 - Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.
Completed NCT03022253 - Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates Phase 3
Recruiting NCT02380040 - Plethismographic Perfusion Index in Neonates N/A