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Population Pharmacokinetics and Dosage Individualization of Paracetamol and Ibuprofen in Children With PDA

Patent Ductus Arteriosus Clinical Trial

Official title:
Population Pharmacokinetics and Dosage Individualization of Paracetamol and Ibuprofen in Preterm Neonates and Infants With Patent Ductus Arteriosus

Clinical Trial Summary

The investigator's purpose is to study the population pharmacokinetics of paracatamol and ibuprofen in neonates with patent ductus arteriosus (PDA) and assess the feasibility of dosage individualization.

Clinical Trial Description

The investigator's purpose is to study the population pharmacokinetics of paracatamol and ibuprofen in neonates with patent ductus arteriosus (PDA) and assess the feasibility of dosage individualization. In this study, the investigator will detect drug concentration in plasma and other clinical test to construct population pharmacokinetic models. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04397913
Study type Observational
Source Shandong University
Contact Wei Zhao, Ph.D
Phone 053188383308
Email zhao4wei2@hotmail.com
Status Recruiting
Phase
Start date May 25, 2020
Completion date May 6, 2023
View Details
See also
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