Patellofemoral Syndrome Clinical Trial
Quadriceps retraining, especially the vastus medialis oblique muscle strengthening, plays an
important role in clinical management of patellofemoral pain syndrome. Vastus medialis
oblique muscle roles as a dynamic stabilizer during the functional knee movement. It can
generate a medial pulling force to patella against the lateral pulled by vastus lateralis.
Thus it improves the patellofemoral joint compression force, reduces the knee pain,
increases functional abilities, and patients’ quality of life.
Could vastus medialis oblique be isolation by way of specific exercise without or minimize
the recruitment of vastus lateralis? According to human anatomy, vastus medialis oblique
muscle origin from hip adductor magnus tendon, thus if incorporate hip adduction with knee
extension as a selective means of training needs more researches. However, literature search
shows that there are only a lot of EMG studies, so we need further clinical research to
prove the treatment effect of this kind of strategy.
The purpose of the study is to investigate the treatment effects of hip adduction combine
knee extension exercise in patients with patellofemoral pain syndrome. We use muscle
morphology of quadriceps muscle, pain, and functional abilities as the main outcome
measures. Besides, we will make further compare with traditional knee extension exercise.
The first hypothesis of the study is that patients with patellofemoral pain syndrome will
get improvement in muscle morphology of quadriceps muscle, pain, and functional abilities
after hip adduction combine knee extension exercise training . The second hypothesis is that
patients with patellofemoral pain syndrome who receive hip adduction combine knee extension
exercise training will get more improvement in muscle morphology of quadriceps muscle, pain,
and functional abilities than patients who receive traditional knee extension exercise
training.
90 patients with patellofemoral pain syndrome who less than 50 years old will be included in
this study, and randomly distributed to hip adduction combine knee extension exercise group,
knee extension exercise group, and control group. Following 8 weeks exercise training by an
experimental physical therapist, ultrasound measurement of muscle thickness and
cross-sectional area of vastus medialis oblique muscle, vastus lateralis muscle, and rectus
femoris muscle component of quadriceps, 10cm-VAS patellofemoral joint pain evaluation,
including VAS-U, VAS-W, and VAS-activity, and Lysholm scale scores will be measured. A
two-way mixed ANOVA will be used to compare the mean differences between theses three
groups.
The study is aimed to provide an clinical evidence for evidence-based practice of
rehabilitation in patients with patellofemoral pain syndrome.
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Educational/Counseling/Training
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