5 Year Follow-up of Adolescents With Knee Pain

Patellofemoral Pain Syndrome Clinical Trial

Official title:

5 Year Follow-up of Adolescents With Knee Pain - a Prospective Cohort Study of 504 Adolescents

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02873143
• Other study ID #: 2011-0020
• Status: Completed
• Phase: N/A
• First received: August 16, 2016
• Last updated: January 26, 2017
• Start date: September 2016
• Est. completion date: January 2017

Study information

• Verified date: January 2017
• Source: Aalborg University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown.

In 2011, a cohort of 2200 adolescents aged 15 to 19 years answered an online questionnaire on musculoskeletal pain. Of these, 504 reported knee pain, and 153 of these were clinically diagnosed with PFP. Now, after 5 years, the 504 adolescents, as well as 252 randomly selected adolescents who did not report knee pain in 2011, will be contacted again to gain insights into their prognosis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 540
• Est. completion date: January 2017
• Est. primary completion date: December 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 15 Years to 19 Years

Eligibility

From the 504, 153 were diagnosed with PFP, the criteria for which included:

• insidious onset of anterior knee or retropatellar pain for longer than 6 weeks that was provoked by at least 2 of the following: prolonged sitting or kneeling, squatting, running, hopping, or stair climbing; tenderness on palpation of the patella; pain when stepping down; or double-leg squatting.

Exclusion criteria were:

• concomitant injury or pain from the hip, lumbar spine, or other knee structures

• self-reported patellofemoral instability

• knee joint effusion.

Related Conditions & MeSH terms

• Knee Pain
• Patellofemoral Pain Syndrome

Intervention

Other:
• No intervention
No intervention

Locations

Country	Name	City	State
n/a

Sponsors (4)

Lead Sponsor	Collaborator
Aalborg University	Copenhagen University Hospital, Denmark, Research Unit for General Practice in Aalborg, University of Southern Denmark

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Knee pain during the last week	All subjects are asked if they experienced knee pain during the last week	5 years
Secondary	Knee pain during the last 30 days	Did you experience knee pain during the last 30 days?	5 years
Secondary	Frequency of knee pain	Frequency of knee pain divided into (almost daily, several times per week, weekly, monthly, rarely, never	5 years
Secondary	When did your knee pain resolve		5 years
Secondary	Pain in other regions of the body		5 years
Secondary	Seeking medical attention for your knee pain		5 years
Secondary	Previous treatments for your knee pain		5 year
Secondary	Use of pain medication		5 years
Secondary	Worst pain last week	Measured on a numeric rating scale	5 years
Secondary	Knee Injury and Osteoarthritis Outcome score		5 years
Secondary	Health-related quality of life	Measure with the EQ-5D-3L	5 years
Secondary	The influence of knee pain on choice of activity level, mood, choice of education and professional career		5 years
Secondary	Physical activity level	Measured with the IPAQ	5 years
Secondary	Number of sports participation per week		5 years
Secondary	The effect of knee pain on sports participation		5 years
Secondary	Self-reported sleep problems	Assessed by asking three questions related to: trouble falling asleep, wake several times per night and trouble staying asleep.	5 years