Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

Patellofemoral Pain Syndrome Clinical Trial

Official title:

Comparison of Early Hip Strengthening to Early Quadriceps Strengthening in the Treatment of Females With Patellofemoral Pain

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00445224
• Other study ID #: 07-0138-F2L
• Status: Completed
• Phase: Phase 2
• First received: March 6, 2007
• Last updated: July 30, 2015
• Start date: January 2008
• Est. completion date: January 2010

Study information

• Verified date: July 2015
• Source: University of Kentucky
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS, there have been few randomized clinical trials comparing isolated hip to isolated quadriceps strengthening. The purpose of this study is to determine how different exercises affect pain, strength, muscle activity, and function in female subjects with patellofemoral pain. The researchers hypothesize that females diagnosed with PFPS who initially participate in a hip strengthening program will report a greater perceived level of function, greater strength, less pain, and improved neuromuscular activity than those who participate in a progressive quadriceps strengthening intervention.

Description:

Methods: Thirty-three females with PFPS will perform either initial hip strengthening (hip group) or initial quadriceps strengthening (quad group) for 4 weeks, prior to 4 weeks of a similar program of functional weight-bearing exercises. Self-reported pain, function, and functional strength were measured. Isometric strength was assessed for hip abductors, external rotators, and knee extensors. A mixed-model analysis of variance will be used to determine group differences over time.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 33
• Est. completion date: January 2010
• Est. primary completion date: January 2010
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 15 Years to 35 Years

Eligibility

Inclusion Criteria:

• anterior or retropatellar knee pain reported during at least 2 of the following activities: ascending and descending stairs, hopping and running, squatting, kneeling, and prolonged sitting

• insidious onset of symptoms not related to trauma

• pain with compression of the patella

• pain on palpation of the patellar facets

Exclusion Criteria:

• symptoms present for less than one month

• clinical evidence of other knee pathology

• history of recent knee surgery within past one year

• history of patellar dislocations or subluxations

• current significant injury affecting other lower extremity joints

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Patellofemoral Pain Syndrome

Intervention

Other:
• Hip Progressive Resistive Exercise
Hip Progressive Resistance Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening hip abduction ad external rotation musculature.
• Quad Progressive Resistive Exercises
Quad Progressive Resistive Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening quadriceps musculature with straight leg raises and quadriceps isometrics.

Locations

Country	Name	City	State
United States	University of Kentucky	Lexington	Kentucky

Sponsors (1)

Lead Sponsor	Collaborator
University of Kentucky

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Visual Analog Pain Scale (Describing Worst Pain Felt During the Past Week)	0 to 10 cm line with 0 representing no pain and 10 representing severe pain	weekly	No
Primary	Subjective Function by Lower Extremity Functional Scale Report Form		Baseline, Mid-Intervention, and Post-Intervention	No
Primary	Visual Analog Pain Scale	Visual analog pain scale at end of intervention. 0 to 10 cm line with 0 representing no pain and 10 representing severe pain	8 week	No
Secondary	Strength by Isometric Dynamometer		Baseline, Mid, and Post-Intervention	No
Secondary	Neuromuscular Activity by Surface Electromyographical Amplitude During Stair Descent		Baseline, Mid and Post-Intervention	No
Secondary	Objective Function by Step-down Task for 30 Seconds		Baseline, Mid, and Post-Intervention	No
Secondary	Hip Abduction Strength	Side lying Hip Abduction maximal muscular contraction with a hand held dynamometer	8 week	No