Patellar Instability Clinical Trial
Official title:
Pediatric and Adolescent Patellar Instability
This is a multi-center, randomized controlled clinical trial, the purpose of which is to determine if patients age 25 and younger who undergo medial patellofemoral ligament (MPFL) reconstruction have lower rates of recurrent instability compared to those treated non-operatively. The MPFL is a ligament that stabilizes the kneecap, and maintains its proper position in the groove on the femur (thighbone). Instability refers to a situation in which the kneecap moves out of place, or dislocates. When instability is recurrent, it occurs more than once in the same knee.
A total of 240 patients will be enrolled across participating sites around the country. These sites currently include: The Hospital for Special Surgery, Oregon Health and Science University, Inova Sports Medicine, and Mayo Clinic. Patients are randomly assigned to one of two treatment groups. Patients assigned to the "stabilization" group will undergo surgery to reconstruct the MPFL using either a hamstring tendon that is your own or one obtained from a donor. Patients assigned to the "conservative" group will be treated with physical therapy, and possibly a simple knee arthroscopy if you are found to have a loose fragment on x-ray or MRI. All patients will be required to return for follow-up visits, which will continue over the course of 5 years. During these visits, patients will be examined, asked to answer questions about their surgery and general health, and have imaging (x-ray and MRI) performed on the knee. All patients enrolled in this study will undergo a standardized, intensive rehabilitation protocol. The investigators anticipate that all patients may benefit from extensive rehabilitation, including strengthening and return to sport training. The knowledge gained from this study may benefit others in the future. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05184439 -
Evaluation of Adductor Magnus Tenodesis in Patients With Recurrent Patellar Dislocation.
|
||
| Terminated |
NCT02998372 -
Computational Simulation of Patellar Instability
|
||
| Completed |
NCT03983213 -
The Comprehensive Assessment in Children After Surgical Treatment of Patellar Recurrent Dislocation.
|
||
| Recruiting |
NCT04849130 -
Comparison of Dynamic and Static Medial Patellofemoral Ligament Operation Technique for Recurrent Patellar Dislocation
|
N/A | |
| Recruiting |
NCT04653753 -
Assessment of the Safety and Performance of a Patellofemoral Brace
|
N/A | |
| Recruiting |
NCT05029505 -
The Caton-Deschamps Index Reliability in Patellar Stabilization Surgery.
|
||
| Terminated |
NCT00816647 -
A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction
|
N/A | |
| Completed |
NCT04438109 -
Clinical Outcome of the Dynamic Reconstruction of the Medial Patellofemoral Ligament (MPFL)
|
||
| Completed |
NCT04378491 -
Clinical and Functional Outcome After Lateral Trochlear Lengthening Osteotomy Lateral Trochlear Lengthening Osteotomy
|
||
| Completed |
NCT03304119 -
Torsion of the Tibial Tuberosity, a New Factor of Patellar Instability?
|