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Partial Seizures clinical trials

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NCT ID: NCT04257604 Completed - Partial Seizures Clinical Trials

A Study of Perampanel as Add-on Therapy in Adult and Adolescent Participants With Focal Seizures

Start date: January 3, 2016
Phase:
Study type: Observational

The primary objective of the present study will be to assess the effectiveness of add-on perampanel in participants with focal seizures in a real-life clinical setting.

NCT ID: NCT03340064 Completed - Partial Seizures Clinical Trials

A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging From 1 Month to Less Than 4 Years of Age

PEACH
Start date: November 30, 2017
Phase: Phase 3
Study type: Interventional

This is a study to confirm the efficacy of levetiracetam as adjunctive treatment or as monotherapy in pediatric epilepsy subjects aged 1 month to less than 4 years of age with partial seizures.

NCT ID: NCT01954121 Completed - Epilepsy Clinical Trials

Open-label, Randomized, Active-controlled Study of LEV Used as Monotherapy in Patients With Partial-Onset Seizures

Start date: September 2013
Phase: Phase 3
Study type: Interventional

To demonstrate the non-inferiority of Levetiracetam (1000 mg/day) versus Carbamazepine Immediate-Release (400 mg/day) used as monotherapy for at least 6 months in a Chinese population with newly or recently diagnosed Epilepsy who are experiencing Partial-Onset Seizures (POS).

NCT ID: NCT01630057 Completed - Partial Seizures Clinical Trials

Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug

Start date: September 2009
Phase: Phase 4
Study type: Interventional

An open-label, randomized, multi-centre, superiority study to assess that, in patients who respond to zonisamide added as third drug after failure of a two-drug combination therapy, the triple therapy is superior to the conversion to a double therapy including zonisamide.

NCT ID: NCT01392768 Completed - Epilepsy Clinical Trials

Efficacy and Safety of Levetiracetam in Partial Seizures Control, With or Without Secondary Generalization

Mozart
Start date: January 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether levetiracetam as adjunctive therapy is effective in the treatment of partial seizures, with or without secondary generalization, associated with refractory focal epilepsy.

NCT ID: NCT01262677 Completed - Epilepsies, Partial Clinical Trials

Once-A-Day Pregabalin For Partial Seizures

Start date: February 17, 2011
Phase: Phase 3
Study type: Interventional

Approximately 30% percent of subjects with partial seizures are refractory to treatment with single or combination antiepileptic drugs. The present study will compare the efficacy of two different dosages of pregabalin CR dosed once daily as compared to placebo, when used as adjunctive therapy in subjects requiring adjunctive therapy for partial onset epilepsy, using a randomized, parallel group design.

NCT ID: NCT01136954 Completed - Partial Seizures Clinical Trials

A Study to Assess the Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Extension Study)

Start date: July 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the long-term safety and efficacy of zonisamide used as an adjunctive treatment in pediatric subjects treated with 1 or 2 other anti-epileptic drugs (AEDs).

NCT ID: NCT01063764 Completed - Epilepsy Clinical Trials

An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures

Start date: January 2010
Phase: Phase 3
Study type: Interventional

Objective of the First Period: To evaluate the efficacy of Levetiracetam dry syrup at doses up to a maximum of 60 mg/kg/day or 3000 mg/day used as an adjunctive therapy in Japanese pediatric patients (4 to 16 years) with uncontrolled partial seizures despite treatment with 1 or 2 anti-epileptic drug(s).

NCT ID: NCT00537238 Completed - Partial Seizures Clinical Trials

Pregabalin Versus Levetiracetam In Partial Seizures

Start date: October 2007
Phase: Phase 3
Study type: Interventional

This study will compare pregabalin and levetiracetam in patients with partial seizures. It will also evaluate the safety and tolerability of pregabalin and levetiracetam in these patients.

NCT ID: NCT00327717 Completed - Partial Seizures Clinical Trials

Evaluating the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures

Start date: September 2006
Phase: Phase 3
Study type: Interventional

The objectives of this trial are to evaluate the safety and efficacy of Zonisamide as adjunctive therapy in medically refractory patients receiving other antiepileptic drugs (AEDs).