Role of Methylene Blue in Parotid Surgery

Parotid Tumor Clinical Trial

Official title: Role of Methylene Blue Dye in Identification of Facial Nerve in Parotid Surgery

Status Not yet recruiting

Clinical Trial Summary

usefulness of the methylene blue staining for identification of facial nerve in parotid gland surgery

Clinical Trial Description

The specific surgical morbidity remains significant in parotid gland surgery. In addition to temporary facial weakness and permanent facial nerve injury, postparotidectomy depression and Frey's syndrome (gustatory sweating) are specific for this type of surgery. To reduce the surgical morbidity, several modifications of parotidectomy have been implemented but postsurgical complications remain especially facial nerve injury . To overcome this difficulty, an identification method might be used such as preoperative intravital staining of the gland with methylene blue (MB).

Although MB staining is not designed to be used as a sole technique, it can be combined with other techniques such as identification of the anatomic landmarks. MB staining is simple, inexpensive, and not time consuming technique.It is an indirect facial nerve identification technique, because there is no nerve handling,thus decreasing iatrogenic nerve impairment.After injection of the parotid gland with MB dye, fine white nerve fibers can be observed . Tumors in the parotid gland are also easily seen because they are not stained and will be visible in the surgical field. ;

Related Conditions & MeSH terms

• Parotid Neoplasms
• Parotid Tumor

• NCT number: NCT05401370
• Study type: Interventional
• Source: Assiut University
• Contact: Ismail Ali Mohamed
• Phone: 01124153353
• Email: ismailali203040@gmail.com
• Status: Not yet recruiting
• Phase: N/A
• Start date: June 2022
• Completion date: December 2023