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Parotid Neoplasms clinical trials

View clinical trials related to Parotid Neoplasms.

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NCT ID: NCT05152056 Completed - Parotid Tumor Clinical Trials

MRI and Fine Needle Aspiration in the Diagnosis of Parotid Tumors

Parotid
Start date: November 15, 2021
Phase:
Study type: Observational

What value is given to MRI diffusion and perfusion sequences in the diagnosis of parotid tumors? Is a fine needle aspiration associated with MRI systematically necessary? The aim of the research is to study the performance of diffusion and perfusion MRI sequences in the diagnosis of parotid tumors on a large series of cases.

NCT ID: NCT04803032 Completed - Surgery Clinical Trials

Trident Landmark as a Safe and Easy Method for Facial Nerve Trunk Identification During Superficial Parotidectomy

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The parotid has a close relationship with the extra temporal course of the facial nerve. The study aimed to evaluate the accuracy and safety of trident landmark during superficial parotidectomy in the identification of the facial nerve trunk.

NCT ID: NCT04420689 Completed - Surgery Clinical Trials

A Study of ALM-488 to Highlight Nerves in Patients Undergoing Head & Neck Surgery

Start date: June 18, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Phase 1/2 study of ALM-488 to highlight nerves in patients undergoing head & neck surgery.

NCT ID: NCT04296266 Completed - Clinical trials for Submandibular Gland Tumor

Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery

Start date: February 2016
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is determine salivary gland disposition of d-limonene, the primary component in citrus peel and a common dietary supplement. Salivary gland tissue and saliva will be collected to determine concentration of d-limonene and its metabolites in these tissues.

NCT ID: NCT03822728 Completed - Clinical trials for Facial Nerve Paresis

Intra-parotid Facial Nerve Imaging in Parotidectomy

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

In this study, the investigators will evaluate the clinical usefulness of 3 dimensional double echo steady state MRI (3D-DESS MRI) for functional preservation of the facial nerve during parotidectomy. Preoperative 3D-DESS MRI imaging can provide information about the anatomical relationship between the tumor and the facial nerve in the parotid gland. Because the risk of postoperative facial weakness is relatively high in the deep-seated parotid tumors, the investigators will exclude the patients with the superficial parotid tumors (determined by preoperative CT or US) and only include the patients with deep seated parotid tumors in this trial. The main outcome of our study is the incidence of immediate postoperative facial weakness, and the secondary outcome is the incidence of facial weakness at postoperative 6 months.

NCT ID: NCT02527226 Completed - Facial Paralysis Clinical Trials

Post-parotidectomy Facial Paresis: Intraoperative and Postoperative Factors

Start date: August 2015
Phase: N/A
Study type: Interventional

This is a protocol to govern the prospective trial of facial nerve monitoring in patients undergoing parotidectomy with an eye towards interpreting if the facial nerve monitor provides useful information to operating surgeons and if the information provided by the facial nerve monitor can predict degrees of postoperative facial nerve paresis. Additionally, the study will determine if performing daily facial rehabilitation exercises provides a benefit in reducing time to recovery of temporary post-parotidectomy paresis.

NCT ID: NCT01983176 Completed - Clinical trials for Postoperative Complications

Retrospective Clinical Outcome of Parotid Tumor Surgery

Start date: October 2013
Phase: N/A
Study type: Observational

The aim of this study was to determine the histopathological results of parotid tumors and postoperative complications after partial superficial or total parotidectomy with facial nerve dissection and superficial musculoaponeurotic system reconstruction.

NCT ID: NCT01414790 Completed - Parotid Tumor Clinical Trials

The Use of Human Acellular Dermal Matrix to Improve Infraauricular Depressed Deformities and Frey's Syndrome

Start date: January 2004
Phase: Phase 3
Study type: Interventional

The aim of the study was to explore whether human acellular dermal matrix (ADM) implantation could prevent infraauricular depressed deformities and Frey's syndrome following total parotidectomy.

NCT ID: NCT00405405 Completed - Clinical trials for Head and Neck Cancer

Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer

Start date: December 2006
Phase: Phase 1
Study type: Interventional

To determine a safe and effective doses of two biologic drugs, erlotinib and bevacizumab when used with chemotherapy and radiation therapy in advanced head and neck cancer