Repetitive Transcranial Magnetic Stimulation for Freezing of Gait

Parkinsonian Disorders Clinical Trial

Official title:

Repetitive Transcranial Magnetic Stimulation for Freezing of Gait

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01853150
• Other study ID #: 2013-022
• Status: Completed
• Phase: N/A
• Start date: April 2013
• Est. completion date: July 2018

Study information

• Verified date: July 2018
• Source: Dongtan Sacred Heart Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Freezing of gait (FOG) means that patients cannot walk without any known causes, other than parkinsonism, which is very disabling symptom. Patients descirbe their feeling of the feet suddenly being glued to the floor. Transcranial magnetic stiumation is a noninvasive procedure using electromagnetic induction to stimulate brain. Transcranial magnetic stiumation (rTMS) can selectively change brain activity to enhance desired effects. The aim of this study is to the therapeutic effect of rTMS for the FOG.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: July 2018
• Est. primary completion date: July 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• Parkinson's disease or Primary progressive freezing of gait

• age 18 and older

• Freezing of gait

Exclusion Criteria:

• pregnant or any, other medical, surgical, neurological or psychiatric conditions

• other restrictions which prevent you from undergoing TMS recording, such as; surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), and/ or heart/cardiac lines

• any past or current history of seizure disorder or epilepsy

• unable to give informed consent

Related Conditions & MeSH terms

• Parkinsonian Disorders

Intervention

Device:
• rTMS Motor cortex

• rTMS Supplementary motor area

Locations

Country	Name	City	State
Korea, Republic of	Dongtan Sacred Heart Hospital	Hwaseong Si	Gyeonggi-Do

Sponsors (1)

Lead Sponsor	Collaborator
Dongtan Sacred Heart Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The number of steps	The number of steps during the stand-walk-sit (SWS) test	2 days
Secondary	The completion time during the SWS test		2 days
Secondary	Freezing episodes of gait trajectory		2 days
Secondary	Patient and Clinical Global Impression Scale		2 days