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Health Outcomes of Parents With Cystic Fibrosis — HOPeCF  

Cystic Fibrosis Clinical Trial

Official title:
Health Outcomes of Parents With Cystic Fibrosis (HOPeCF): A Retrospective Analysis of Impact of Parenthood on Lung Function

Clinical Trial Summary

This project will determine the health impact of parenthood on people with cystic fibrosis (CF). The study team will use retrospective data to provide relatively immediate evidence on parenthood's effect on pulmonary health.

Clinical Trial Description

This co-funded study sponsored by the National Institutes of Health and the CF Foundation (CFF) will seek to determine the health impact of parenthood on people with CF in the era of CF transmembrane conductance regulator (CFTR) modulators. To provide relatively immediate evidence on parenthood's effect on pulmonary health and the influence of the introduction and use of all available CFTR modulators, in Aim 1 the study team will assess changes in pre- vs. intra-parenthood percent predicted forced expiratory volume in 1 second (ppFEV1) in a retrospective longitudinal cohort study linking CFF patient registry (CFFPR) data with cross-sectional surveys collected from 249 new parents attending participating United States CF centers between 2012-2022. The study team will identify predictors and timing of lung function loss using 747 non-parents from participating centers as a comparison group and examine the impact of CFTR modulators on parental health. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05829694
Study type Observational
Source University of Pittsburgh
Contact Olivia M Stransky, MPH
Phone 412-648-4701
Email stranskyom@upmc.edu
Status Recruiting
Phase
Start date July 12, 2023
Completion date July 2024
View Details
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