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Parenteral Nutrition clinical trials

View clinical trials related to Parenteral Nutrition.

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NCT ID: NCT00321165 Completed - Sepsis Clinical Trials

The AOT (Acridine Orange and Taurolidine) Trial

Start date: June 2006
Phase: Phase 3
Study type: Interventional

Total parenteral (intravenous) nutrition in the home setting (Home TPN or HPN) is a life saving strategy in patients who suffer from severe intestinal failure. Unfortunately, this treatment modality remains complicated by the development of frequent infectious complications. This especially relates to the device that is used to establish venous access, mostly a catheter (Hickman-Broviac type) or a port-a-cath. Taurolodine is an antimicrobial agent without any known side effects or resistance-related problems that holds promise as an effective antibiotic lock solution to prevent catheter infections, as demonstrated recently in a pilot study in HPN patients [Jurewitsch, 2005]. In addition, recently a test has been described which may enable to confirm a suspected diagnosis of central line infection within one hour, the so-called Acridine Orange Leukocyte Cytospin test (AOLC) [Bong, 2003]. For this test, blood that is drawn from the central line is stained with the fluorescent dye acridine orange. Next, microscopic evaluation for the presence of micro-organisms takes place. Implementation of this test might enable to start treatment of the infection and prevent unnecessary removal of non-infected central lines without the necessity to several days wait for culture results.

NCT ID: NCT00292279 Completed - Clinical trials for Parenteral Nutrition

The Impact of Omega-3 Fat Emulsion on Clinical Outcome of Post-Operative Cancer Patients

Start date: June 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate clinical safety and effect of Omega-3 fat oil emulsion on outcome in post-operative cancer patients.