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Papilloma clinical trials

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NCT ID: NCT01757392 Completed - Clinical trials for Human Papilloma Virus

Candin Safety & Efficacy Study for the Treatment of Warts

Start date: September 2012
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to determine the safety of Candin® (Candida albicans Skin Test Antigen) at a 0.3 ml dose level at up to 6 monthly injections for treating common warts (Verruca vulgaris).

NCT ID: NCT01729429 Completed - Clinical trials for Human Papilloma Virus-Related Cervical Carcinoma

An Intervention Promoting HPV Vaccination in Safety-net Clinics

Start date: May 2010
Phase: N/A
Study type: Interventional

This randomized controlled trial is designed to evaluate whether a behavioral intervention that includes three components: 1) reminder letters and education materials delivered before the clinic visit, 2) telephone recalls after the visit for those who originally decline the vaccine, and 3) telephone reminders for those who miss the 2nd and/or 3rd doses, increases 1 and 3 dose coverage of the human papillomavirus (HPV) vaccine series among adolescent girls attending four Parkland primary care clinics in Dallas county. Hypothesis 1: Investigators expect higher 1 dose HPV vaccine coverage among patients in the Intervention group than those in the General Adolescent Vaccine Brochure group. Hypothesis 2: Investigators expect significantly higher 1 dose HPV vaccine coverage among patients in the Intervention group who initially declined the vaccine than those in the General Adolescent Vaccine Brochure group who initially declined. Hypothesis 3: Investigators expect significantly higher 3 dose HPV vaccine coverage among the Intervention group than those in the General Adolescent Vaccine Brochure group.

NCT ID: NCT01637194 Completed - Clinical trials for Recurrent Colon Cancer

Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer

Start date: November 2008
Phase: Phase 1
Study type: Interventional

This phase I trial studies the side effects and best dose of cetuximab when given together with everolimus in treating patients with metastatic or recurrent colon cancer or head and neck cancer. Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of the tumor to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Everolimus may stop the growth of tumor cells by blocking blood flow to the tumor. Giving cetuximab together with everolimus may be an effective treatment for colon cancer or head and neck cancer

NCT ID: NCT01567813 Completed - Clinical trials for Human Papilloma Virus Infection

Post-Licensure Study of the Safety of GARDASILâ„¢ in Males (V501-070)

Start date: June 23, 2011
Phase:
Study type: Observational

This is a post-licensure safety observation cohort study to describe the general safety of GARDASILâ„¢ (a quadrivalent human papillomavirus vaccine) in males.

NCT ID: NCT01539668 Completed - Prevention Clinical Trials

Hybrid Capture Test on Mobile Unit Program to Improve Cervical Cancer Screening in Brazilian Rural and Remote Areas

careHPV
Start date: March 2012
Phase: Phase 0
Study type: Observational

This study evaluates the women cervical samples through molecular tests in order to: 1. Deploy the test careHPV (hybrid capture test) in mobile unities of the Barretos Cancer Hospital to evaluate their performance;

NCT ID: NCT01375868 Completed - Clinical trials for Squamous Papilloma of the Larynx

Effect of Vaccination in Patients With Recurrent Respiratory Papillomatosis

Start date: October 2011
Phase: Phase 3
Study type: Interventional

Vaccines against human papillomaviruses are now commercially available. One of the commercial vaccine contains antigens of both LR HPV types which cause virtually all cases of RRP. Clinical trials have documented the safety and immunogenicity of this vaccine as well as its effectiveness in prevention of incident and persistent infection of the vaccinal types as well as a development of lesions caused by these types. After vaccination the antibodies level increases dramatically and the high levels of antibodies are present in the blood still after 6 years. Furthermore, the neutralization antibodies to the vaccinal antigens have been detected in the cervical mucus of vaccinated women. The preliminary data are now available showing the presence of HPV-specific antibodies in the oral cavity in women after vaccination. The level of antibodies has been dependent on time since vaccination.

NCT ID: NCT01304966 Completed - Clinical trials for Human Papilloma Virus

Human Papillomatosis Genotyping of Children in Thailand

Start date: March 2011
Phase: N/A
Study type: Observational

The purpose of the present study was to identify risk factors for more severe juvenile Recurrent Respiratory Papillomatosis (RRP) through prospective evaluation of a pediatric population in Thailand by the employing a protocol that includes staging of disease severity using above mentioned staging system at the time of each endoscopic debridement, as well as human papilloma virus (HPV) genotyping.

NCT ID: NCT01206556 Completed - Clinical trials for Papilloma Virus, Human

IMPAACT P1085: Human Papilloma Virus (HPV) Type-Specific Antibody

HPV
Start date: May 2010
Phase: N/A
Study type: Observational

This study is being done to evaluate how long the immune response from the Human Papilloma Virus (HPV) vaccine you / your child received persists. The immune response occurred after immunization and is what protects you/your child from HPV disease. You / your child received this vaccine as part of an earlier study (P1047). The vaccine is called Human Papillomavirus Vaccine (QHPV Vaccine, also known as GARDASIL®). The study will check to see if the protective effects (called "antibodies") produced by the vaccine have lasted, and for how long these effects will continue to last. You will not be given any medications or vaccines as part of this follow-up study.

NCT ID: NCT01192282 Completed - Clinical trials for Human Papilloma Virus

Typing of Human Papilloma Virus (HPV) From Female Genital Warts

Start date: April 2010
Phase: N/A
Study type: Observational

This is a longitudinal observational study of women presenting to Groote Schuur Hospital with genital warts. The study will evaluate the socio-demographic characteristics of the women using a structured questionnaire. It will also document the site and extend of the genital warts and genotyping will be performed on the warts. HIV status will be determined with patient consent, treatment modalities will be documented as will the outcome of treatment over a 6 month's period. Risk factors for recurrence or failure of treatment will be analysed as will the costs of treating women with genital warts.

NCT ID: NCT01030562 Completed - Clinical trials for Papilloma Viral Infection

Immunogenicity of Off-Schedule Dosing of HPV Vaccine

Start date: June 2, 2010
Phase:
Study type: Observational

The purpose of this study is to gain a better understanding of the body's response to a human papillomavirus (HPV) (sexually transmitted disease), vaccine and booster shot. The study will also determine factors related to adolescents not following vaccination schedules. The HPV vaccine requires 3 doses (shots). Girls sometimes receive the 3 shots at the recommended time and sometimes girls receive the shots at non-recommended times. This study will evaluate if getting the shots at non-recommended times affects the level of protection provided by the vaccine. Participants will include about 1400 girls 9-17 years old receiving a third dose of HPV vaccine from their primary care clinician. The parent/legal guardian of each subject may answer a questionnaire related to the vaccine schedule. Study procedures include: medical history, questionnaires and blood draws. Participants will be involved in the study for about 6 months from time of enrollment.