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Clinical Trial Summary

This is a prospective cohort study to test Minimally Invasive Treatments of the Thyroid (MITT) as potential alternative to surgery in patients with Papillary Thyroid MicroCarcinoma (PTMC)


Clinical Trial Description

Image-guided thermal ablations have been successfully applied in the treatment of several type of tumors, and have been recently proposed as a potential alternative to surgery also in patients with thyroid diseases, and named "Minimally Invasive Treatments of the Thyroid (MITT)". These minimally invasive treatments, compared to surgical treatment have similar efficacy, fewer complications, better quality of life, and better cosmetic outcomes. These procedures allow precise delivery of the heat locally to the lesion, sparing the surrounding thyroid tissue, and thus minimizing the invasiveness of the treatment and the impact on thyroid function. This study aim to establish a prospective registry of the cases of patients treated with MITT for a Papillary Thyroid MicroCarcinoma (PTMC), in order to validate the safety of the procedure and to set the basis for collecting long term results in a large cohort of patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06333587
Study type Observational
Source European Institute of Oncology
Contact Giovanni Mauri
Phone +390294372691
Email giovanni.mauri@ieo.it
Status Recruiting
Phase
Start date October 10, 2022
Completion date December 31, 2035

See also
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Active, not recruiting NCT04129411 - Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation N/A
Recruiting NCT03808779 - A Multicenter Trial of Radiofrequency Ablation vs. Surgery as Treatment of Papillary Thyroid Microcarcinoma. N/A
Not yet recruiting NCT04376203 - Microbiome and Papillary Thyroid Microcarcinoma
Completed NCT01648569 - Long-term Outcomes of Total Thyroidectomy Versus Less Than Total Thyroidectomy for Papillary Thyroid Microcarcinoma N/A
Recruiting NCT03432299 - Radiofrequency Ablation of Low Risk Papillary Thyroid Microcarcinoma N/A