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Pandemic Influenza clinical trials

View clinical trials related to Pandemic Influenza.

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NCT ID: NCT06046092 Recruiting - Influenza A Clinical Trials

H7HLAII DNA Influenza Vaccine

H7N9vax-1
Start date: July 15, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess safety and immunogenicity of H7HLAII, a DNA vaccine encoding influenza hemagglutinin (HA) from influenza A/Shanghai/2/2013 (H7N9) directed to cells expressing human leukocyte antigen class II (HLAII) molecules, for prophylaxis of pandemic H7N9 influenza infection in healthy volunteers.

NCT ID: NCT01640691 Completed - Pandemic Influenza Clinical Trials

Immunogenicity and Safety of Pandemic Influenza Vaccine in Healthy Adults

Start date: July 10, 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The objectives of this single arm study are to evaluate the immune response and safety profiles of two injections of an inactivated whole-virion vaccine containing aluminum hydroxide adjuvant, AdimFlu-W (H5N1), against influenza A (H5N1) in healthy adults.

NCT ID: NCT01053143 Completed - Influenza Clinical Trials

Study of Swine-Origin A/H1N1 Influenza Non-Adjuvanted Vaccine in Healthy Adults in India

Start date: January 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and immunogenicity of one dose of A/H1N1 non-adjuvanted pandemic vaccine to support registration of the vaccine in India. Primary Objective: - To describe the safety profile (injection site reactions and systemic events) of the vaccine within 21 days following vaccination, and serious adverse events throughout the study in all subjects Secondary Objectives: - To describe the immune response to the vaccine 21 days after vaccination by hemagglutination inhibition (HAI) testing in all subjects - To describe the antibody persistence 6 months after vaccination by HAI testing in all subjects.

NCT ID: NCT00976469 Completed - Influenza Clinical Trials

A/H1N1 Immunogenicity and Safety in Infants, Children and Adolescents

Start date: September 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the preferred dose of H1N1 pandemic influenza vaccine in a pediatric population, aged 6 months to 17 years, based upon assessments of immunogenicity and safety.

NCT ID: NCT00971906 Completed - Pandemic Influenza Clinical Trials

Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine in Healthy Subjects 18 or More Years of Age

Start date: August 2009
Phase: Phase 3
Study type: Interventional

This present study, randomized, single-blind, dose-ranging, multicenter study, will evaluate immunogenicity, safety and tolerability of two doses of an adjuvanted and not-adjuvanted new swine-origin influenza A/H1N1 virus monovalent subunit vaccine in healthy adult and elderly subjects. A booster dose will be administered 12 months after the first vaccination.

NCT ID: NCT00971542 Completed - Pandemic Influenza Clinical Trials

Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine (Egg-Derived) in Healthy Subjects From 6 Months to 17 Years of Age

Start date: September 2009
Phase: Phase 3
Study type: Interventional

The present study, randomized, single-blind, dose-ranging, multicenter study, will evaluate immunogenicity, safety and tolerability of two doses of adjuvanted and not-adjuvanted new swine-origin influenza A/H1N1 virus monovalent subunit vaccine in healthy children and adolescents. A booster dose will be administered 12 months after the first vaccination.

NCT ID: NCT00971100 Completed - Pandemic Influenza Clinical Trials

Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine in Healthy Subjects From 6 Months to 17 Years of Age

Start date: August 2009
Phase: Phase 3
Study type: Interventional

The present study, randomized, single-blind, dose-ranging, multicenter study, will evaluate immunogenicity, safety and tolerability of two doses of adjuvanted and not-adjuvanted new swine-origin influenza A/H1N1 virus monovalent subunit vaccine in healthy children and adolescents. A booster dose will be administered 12 months after the first vaccination.

NCT ID: NCT00970177 Completed - Pandemic Influenza Clinical Trials

Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine in Healthy Subjects 18 or More Years of Age

Start date: August 2009
Phase: Phase 3
Study type: Interventional

This present study, randomized, single-blind, dose-ranging, multicenter study, will evaluate immunogenicity, safety and tolerability of two doses of an adjuvanted and not-adjuvanted new swine-origin influenza A/H1N1 virus monovalent subunit vaccine in healthy adult and elderly subjects. A booster dose will be administered 12 months after the first vaccination.

NCT ID: NCT00959465 Completed - Influenza Clinical Trials

A/H1N1 Immunogenicity and Safety in Adults

Start date: August 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to obtain immunogenicity and safety data at different dose levels of an investigational H1N1 pandemic influenza vaccine in healthy adults 18 years of age and older.

NCT ID: NCT00950456 Completed - Influenza Clinical Trials

Observational Study to Assess Safety of H1N1 Pandemic Influenza Vaccine

Start date: November 2009
Phase: N/A
Study type: Observational

The purpose of this observational study, which will be initiated as soon as the licensed H1N1 Pandemic Influenza Vaccine is used in a mass vaccination campaign, is to estimate the incidence of any medically-attended adverse events in all vaccinated subjects.