Clinical Trials Logo
  1. Home
  2. Pancreatoduodenectomy
  3. NCT05109143

Efficacy of Rectal Indomethacin in Prevention of Post-operative Pancreatitis After Pancreaticoduodenectomy

Pancreatoduodenectomy Clinical Trial

Official title:
Efficacy of Rectal Indomethacin in Prevention of Post-operative Pancreatitis After Pancreaticoduodenectomy - a Randomized Controlled Trial

Clinical Trial Summary

Pancreatico-duodenectomy is one of the commonly performed procedure for periampullary/distal cholangio/head of pancreas carcinoma. Post operative pancreatitis is an emerging concept, recently being studied as one of the most important contributing factor of Post-operative pancreatic fistula, which is one of the major complication of pancreatoduodenectomy. Rectal indomethacin, a type of non-steroidal anti-inflammatory drug, when given in a single dose has been shown to prevent pancreatitis in patients undergoing ERCP. In this study, we will be administering rectal indomethacin at the time of induction of anesthesia to the experimental arm of the study and compare the results in terms of incidence of post-operative pancreatitis in the two groups.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05109143
Study type Interventional
Source Institute of Liver and Biliary Sciences, India
Contact
Status Completed
Phase N/A
Start date October 17, 2020
Completion date May 31, 2022
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT06289803 - The Application of Probe Confocal Laser Endomicroscopy in Pancreatic Tumor Surgery N/A
Completed NCT02588066 - Pancreatoduodenectomy With or Without Ligamentum Teres Wrap Around Gastroduodenal Artery Stump for Prevention of Pancreatic Hemorrhage N/A
Completed NCT01984216 - Billroth II Versus Roux-en-Y for the Gastrojejunostomy in the Pancreatoduodenectomy N/A
Not yet recruiting NCT06319755 - Characteristics of Intestinal Microbiome Following Pancreatic Surgery
Recruiting NCT05703581 - Application of "Heidelberg Triangle" Dissection in Pancreatoduodenectomy and Distal Pancreatectomy
Not yet recruiting NCT05895214 - Mesopancreas Study in Pancreatic Cancer
Recruiting NCT05668260 - Internal Biodegradable Stent Versus Non-Stent in Patients at High-Risk of Developing Fistula After Pancreatoduodenectomy N/A
Completed NCT03850236 - Neck Division Level and Postoperative Pancreatic Fistula After Pancreaticoduodenectomy
Not yet recruiting NCT03754595 - Application of 2D and 3D Laparoscopy in Laparoscopic Pancreaticoduodenectomy: a Prospective Randomized Clinical Trial N/A
Completed NCT05573399 - Early Oral Feeding for Patients After Pancreaticoduodenectomy
Completed NCT04381702 - Outcome After Laparoscopic Versus Open Pancreaticoduodenectomy