Post ERCP Pancreatitis Prevention in Average Risk Patients

Status Completed

Clinical Trial Summary

Diclophenac potassium and ceftazidime are commercially available drugs that are used in various clinical situations. They are safe and known for years. Diclophenac potassium and Ceftazidime have been used in some studies for the prophylaxis and treatment of pancreatitis and Post-ERCP Pancreatitis (PEP). Diclophenac potassium, together with indometacin is currently standard treatment for prevention of (PEP) while ceftazidime is possible alternative treatment for patients with contraindications for nonsteroidal medicines. The aim of the study is to evaluate the efficacy of Ceftazidime for the prophylaxis of PEP.

Clinical Trial Description

Study type:

Interventional Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: only Investigator Primary Purpose: Prevention Study Phase: Phase 4

Conditions or Focus of the study: Post ERCP pancreatitis

Intervention information

- Intervention Names ERCP

- Arm Information

- Arm 1:Ceftazidime

- Arm 2 (active comparator): Diclophenac potassium ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Pancreatitis

Clinical Trial Details

NCT number	NCT01784445
Study type	Interventional
Source	University Hospital Rijeka
Contact
Status	Completed
Phase	Phase 4
Start date	June 2013
Completion date	February 2015

View Details

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