Clinical Trials Logo
  1. Home
  2. Pancreatitis
  3. NCT01154608
  4. Details
NCT01154608 Clinical Trial

Effect of Enzyme Therapy on Protein Metabolism in Chronic Pancreatitis

Pancreatitis Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01154608
Other study ID # PANCREATITE
Secondary ID
Status Completed
Phase N/A
First received June 30, 2010
Last updated June 30, 2010
Start date April 2005

Study information
Verified date May 2010
Source Institut National de la Recherche Agronomique
Contact n/a
Is FDA regulated No
Health authority France: Health Administration
Study type Interventional

Clinical Trial Summary

Pancreatic exocrine insufficiency is known to impair nutrient absorption, especially fat, but few data exist about protein absorption. We aimed to investigate this question and assess the enzyme substitution efficiency using a sensitive method.

Recruitment information / eligibility
Status Completed
Enrollment 11
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Chronic pancreatitis

- Pancreatic insufficiency

- Enzyme therapy treatment

Exclusion Criteria:

- Hepatic failure

- Pregnancy

- Positive serology to HIV, HCV, AGHbS, gastro-intestinal disease

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Intervention

Drug:
• Creon

Other:
• No enzyme therapy
Current enzyme therapy of the patient is stopped during 7 days

Locations
Country Name City State
France Centre de Recherche sur Volontaires Bobigny

Sponsors (3)
Lead Sponsor Collaborator
Institut National de la Recherche Agronomique National Research Agency, France, Solvay Pharmaceuticals

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary transfer of dietary nitrogen to metabolic pools Yes
See also
  Status Clinical Trial Phase
Recruiting NCT03609944 - SpHincterotomy for Acute Recurrent Pancreatitis N/A
Not yet recruiting NCT04652271 - International Pancreatic Surgery Outcomes Study - PancreasGroup.Org
Completed NCT01441492 - Pancreas Resection With and Without Drains N/A
Recruiting NCT02196935 - Los Angeles Prospective GI Biliary and EUS Series
Completed NCT01476995 - Prognostic Indicators as Provided by the EPIC ClearView N/A
Completed NCT01545167 - The North American Pancreatitis Study N/A
Completed NCT04168801 - Early Oral Refeeding in Mild Acute Pancreatitis N/A
Recruiting NCT03334708 - A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
Completed NCT01824186 - Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy N/A
Terminated NCT00428025 - Diclofenac for the Prevention of Post-ERCP Pancreatitis in Higher Risk Patients Phase 4
Completed NCT00639314 - Trial on the Evaluation of Pylorus-ring in Pancreaticoduodenectomy N/A
Recruiting NCT00160836 - Biliary Tissue Sampling Using a Cytology Brush or the GIUM Catheter Phase 1
Completed NCT00999232 - Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube Phase 4
Completed NCT00121901 - Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis? Phase 3
Terminated NCT00419549 - Efficacy Study of Glyceryl-Trinitrate Patch and Parecoxib (Valdecoxib) for the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography (ERCP) Phase 2/Phase 3
Active, not recruiting NCT05095831 - EUS Shear Wave for Solid Pancreatic Lesions.
Completed NCT03601325 - Acute Pancreatitis: Study of Possible Etiologies and Risk Factors Affecting Outcome
Withdrawn NCT02465138 - A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis Phase 4
Not yet recruiting NCT06133023 - WONDER-02 Trial: Plastic Stent vs. Lumen-apposing Metal Stent for Pancreatic Pseudocysts N/A
Recruiting NCT02971475 - ESWL Versus ESWL and Endoscopic Treatment N/A