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Pancreatitis, Chronic clinical trials

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NCT ID: NCT00744250 Terminated - Cystic Fibrosis Clinical Trials

Intraduodenal Aspiration Study to Assess the Bioavailability of Oral Pancrecarb® Compared to Placebo Control

Start date: August 2008
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to learn about the activity of oral Pancrecarb® (a pancreatic enzyme preparation which contains proteins that help to digest food), administered by mouth as a capsule filled with specially coated granules in patients taking exogenous pancreatic enzyme therapy. Specific enzymes activities will be determined from samples of stomach and intestinal fluids after a standard liquid meal.

NCT ID: NCT00630279 Terminated - Clinical trials for Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis

Dose-ranging Study to Evaluate Efficacy of SLV339 in Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis

Start date: February 2008
Phase: Phase 2
Study type: Interventional

This study is to estimate the efficacy of a number of doses in patients with pancreatic insufficiency

NCT ID: NCT00621283 Terminated - Clinical trials for Chronic Pancreatitis

Secretin Enhanced MRCP for Evaluation of Pancreatic Duct in Pediatric Population

Start date: February 2008
Phase: Phase 1
Study type: Interventional

1. To assess the effect of RG1068 at a dose of 0.2 mcg/kg intravenously (IV) on the diameter of the pancreatic duct when used during Magnetic Resonance Pancreatography. 2. To demonstrate that RG1068-enhanced MRCP improves image quality relative to unenhanced MRCP in patients with unexplained acute recurrent pancreatitis (ARP) and chronic pancreatitis. 3. To evaluate if the use of RG1068-enhanced MRCP improves structural delineation of the pancreatic duct as compared to the non-enhanced MRCP. 4. To assess pancreatic exocrine function by quantifying pancreatic fluid output into the duodenum and the apparent diffusion coefficient of the pancreas.

NCT ID: NCT00620919 Terminated - Clinical trials for Chronic Pancreatitis

Secretin Enhanced Multidetector CT Pancreatography for Evaluation of Known or Suspected Chronic Pancreatitis

Start date: February 2008
Phase: Phase 1
Study type: Interventional

1. To assess the effect of RG1068 at a dose of 0.2 mcg/kg intravenously (IV) on the diameter of the pancreatic duct when used during Multidetector Computed Tomography (MDCT) of the pancreas. 2. To demonstrate that RG1068-enhanced MDCT improves image quality of the pancreas in patients with chronic pancreatitis. 3. To evaluate if RG1068 enhanced MDCT results in improved delineation of structural abnormalities of the pancreatic duct as compared to non-enhanced MDCT.

NCT ID: NCT00500084 Terminated - Clinical trials for Exocrine Pancreatic Insufficiency

Phase III ALTU-135 CP Safety Trial

DIGEST CP
Start date: December 2007
Phase: Phase 3
Study type: Interventional

This is an open-label, single-arm clinical study investigating the long-term safety of ALTU-135 treatment in Chronic Pancreatitis (CP) patients with exocrine Pancreatic Insufficiency (PI).

NCT ID: NCT00469703 Terminated - Clinical trials for Chronic Pancreatitis

Safety and Efficacy Study of Thalomid in Patients With Chronic Pancreatitis

Start date: August 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if Thalidomide (Thalomid) is effective in treating patients with chronic pancreatitis.

NCT ID: NCT00359320 Terminated - Clinical trials for Pancreatic Neoplasms

A Randomized Trial of Two Surgical Techniques for Pancreaticojejunostomy in Patients Undergoing Pancreaticoduodenectomy

Start date: May 25, 2006
Phase: N/A
Study type: Interventional

The purpose of this trial is to determine whether a mucosa-to-mucosa technique of pancreaticojejunostomy will improve the pancreatic fistula rate.