Dual-scopic Pancreatic Necrosectomy (DPN)

Status Recruiting

Clinical Trial Summary

The LPN procedure is performed under general anesthesia. The transperitoneal access to peripancreatic space is via the gastro-colic ligament and greater omentum, effusion and pus is removed by laparoscopic forceps and suction. Laparoscopic cholecystectomy (LC) is performed during the LPN procedure on patients with indication.

The NPN procedure is followed by the standard retroperitoneal approach. After the catheter is exchanged over a guide wire and serially dilated up from 6F to 24F followed by Seldinger technique, the access track to the necrotic cavity is established. A nephroscope is inserted into the cavity through the track for debridement. Using forceps and suction, the peripancreatic solid necrotic tissue and pus is grasped and removed. A large-bore irrigating drain is left in the cavity, with continuous irrigation by warm normal saline solution at a rate of 100-125 ml/h after surgery.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04443595
Study type	Interventional
Source	First People's Hospital of Hangzhou
Contact	Yang Cai
Phone	+8613867136969
Email	caiyang6969@163.com
Status	Recruiting
Phase	N/A
Start date	July 1, 2020
Completion date	December 31, 2025

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03609944` - SpHincterotomy for Acute Recurrent Pancreatitis	N/A
Not yet recruiting	`NCT04652271` - International Pancreatic Surgery Outcomes Study - PancreasGroup.Org
Completed	`NCT01441492` - Pancreas Resection With and Without Drains	N/A
Recruiting	`NCT02196935` - Los Angeles Prospective GI Biliary and EUS Series
Completed	`NCT01476995` - Prognostic Indicators as Provided by the EPIC ClearView	N/A
Completed	`NCT01545167` - The North American Pancreatitis Study	N/A
Completed	`NCT04168801` - Early Oral Refeeding in Mild Acute Pancreatitis	N/A
Recruiting	`NCT03334708` - A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
Completed	`NCT01824186` - Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy	N/A
Terminated	`NCT00428025` - Diclofenac for the Prevention of Post-ERCP Pancreatitis in Higher Risk Patients	Phase 4
Completed	`NCT00639314` - Trial on the Evaluation of Pylorus-ring in Pancreaticoduodenectomy	N/A
Recruiting	`NCT00160836` - Biliary Tissue Sampling Using a Cytology Brush or the GIUM Catheter	Phase 1
Completed	`NCT00121901` - Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis?	Phase 3
Completed	`NCT00999232` - Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube	Phase 4
Terminated	`NCT00419549` - Efficacy Study of Glyceryl-Trinitrate Patch and Parecoxib (Valdecoxib) for the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography (ERCP)	Phase 2/Phase 3
Active, not recruiting	`NCT05095831` - EUS Shear Wave for Solid Pancreatic Lesions.
Completed	`NCT03601325` - Acute Pancreatitis: Study of Possible Etiologies and Risk Factors Affecting Outcome
Withdrawn	`NCT02465138` - A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis	Phase 4
Not yet recruiting	`NCT06133023` - WONDER-02 Trial: Plastic Stent vs. Lumen-apposing Metal Stent for Pancreatic Pseudocysts	N/A
Recruiting	`NCT02971475` - ESWL Versus ESWL and Endoscopic Treatment	N/A