Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to see if SBRT will be a better way to treat pancreas cancer and to find out what effects, good and/or bad, this treatment will have on participants and their cancer.


Clinical Trial Description

The standard treatment for cancer of the pancreas is surgery (if possible), external beam radiation therapy and/or chemotherapy. These standard treatments are not a cure and often extend life by just a few months. Recently, a new approach has been developed, called stereotactic body radiation therapy (SBRT). Based on the results of earlier studies using SBRT, the study doctors at Moffitt feel this is a reasonable alternative to the standard treatment for your disease.

Stereotactic body radiation therapy (SBRT) delivers high radiation doses to the tumor every day for 5 days which gives the usual 5-6 week course of radiation in less than a week. It has also been shown to have much less side effects.

The purpose of this study is to see if SBRT will be a better way to treat pancreas cancer and to find out what effects, good and/or bad, this treatment will have on you and your cancer.

Six patients will be asked to be part of a subgroup called TBRI (Tissue, Blood, Research Imaging). In this subgroup, the investigators want to study if there is early death of tumor cells from the treatment by looking at the tumor using PET/CT scans and biopsies, and by testing your body's white blood cells taken by a procedure called leukapheresis. You do not have to take part in the TBRI subgroup to get treatment on this study with SBRT. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01434550
Study type Interventional
Source H. Lee Moffitt Cancer Center and Research Institute
Contact
Status Withdrawn
Phase N/A
Start date March 2012
Completion date August 2015

See also
  Status Clinical Trial Phase
Completed NCT01673334 - Evaluation of EUS-Guided 22 Gauge Core Biopsy Versus Fine-needle Aspiration for Suspected Pancreatic Neoplasms Phase 4
Recruiting NCT01978808 - Efficiency Study of the EUS-FNA Needles With and Without a Side Port in Pancreatic Masses N/A
Completed NCT01479803 - Comparison of Two Needles (ProCore vs EchoTip) for the Diagnosis of Pancreatic Solid Mass Under EUS Phase 3
Completed NCT02716207 - Phase ǀ Study on Pancreatic Cancer Treated by CyberKnife N/A
Completed NCT03444051 - Comparison of Two Endoscopic Biopsic Needles for Pancreatic Tumors N/A
Recruiting NCT05794048 - METabolic PROFILE of Hepatocarcinoma and Pancreatic Tumors N/A
Recruiting NCT05871164 - Longitudinal, Prospective, French, Multicenter Cohort Study on Pancreatic Radiofrequency
Recruiting NCT03558945 - Clinical Trial on Personalized Neoantigen Vaccine for Pancreatic Tumor Phase 1
Recruiting NCT01969110 - Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy Phase 4
Completed NCT02330497 - Efficacy and Safety of Radiofrequency Ablation in Pancreatic Neuroendocrine and Cystic Tumor N/A
Completed NCT01692873 - Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors N/A
Recruiting NCT04075305 - The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Recruiting NCT04357483 - Effect of Thrombin-containing Collagen-based Hemostatic Matrix Phase 4
Recruiting NCT01698190 - Comparing the Efficacy of Endoscopic FNA vs FNB in Diagnosing Solid Gastrointestinal Lesions N/A
Completed NCT03340844 - Role of CTC´s Spread During Pancreaticoduodenectomy in Patients With Pancreatic and Periampullary Tumors N/A
Withdrawn NCT02534246 - Head to Head Comparison of Two Needles EUS Guided FNB N/A
Not yet recruiting NCT01819961 - Parenteral Fish Oil in Major Laparoscopic Abdominal Surgery Phase 4
Withdrawn NCT02269683 - Robotic vs. Laparoscopic Distal Pancreatectomy for Pancreatic Cancer N/A