Preoperative Endoscopic Pancreatic Stent for Distal Pancreatectomy

Status Recruiting

Clinical Trial Summary

Distal pancreatectomy (DP) with or without splenectomy is commonly indicated for pancreatic body or tail lesions. Postoperative pancreatic fistula (POPF) remains the commonest complication after DP. A pre-operatively placed pancreatic stent across papilla can decrease the pressure gradient between pancreatic duct and duodenum. Therefore, the pancreatic juice flow is redirected from the pancreatic transection plane and leakage from pancreatic stump is much reduced. This study aims to evaluate whether pre-operatively placed pancreatic stent can prevent POPF by a randomized controlled trial.

Clinical Trial Description

A randomised-controlled trial is performed to evaluate the efficacy of preoperative pancreatic duct stenting in preventing post-operative pancreatic fistula after distal pancreatectomy with or without splenectomy. Patients will be randomised to pre-operative stent group or surgery alone group. Pre-operative pancreatic duct stenting will be performed 1-2 weeks before surgery. The stent will be removed 4 weeks after operation. The post-operative pancreatic fistula rate, morbidity, mortality and total length of stay were compared between the 2 groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05297136
Study type	Interventional
Source	Chinese University of Hong Kong
Contact	Kit Fai Lee, MBBS
Phone	35051496
Email	leekf@surgery.cuhk.edu.hk
Status	Recruiting
Phase	N/A
Start date	March 21, 2022
Completion date	May 20, 2026

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