Pancreatic Fistula Clinical Trial
Official title:
Randomized Controlled Trial on Role of Octreotide in Preventing Pancreatic Fistula and Complications After Pancreaticoduodenectomy in Patients With Soft Pancreas
This randomized controlled trial (RCT) aims at assessing the influence of octreotide on pancreatic fistula or complications following pancreatoduodenectomy in patients with soft pancreas. Previously reported trials have included all types of pancreatic resections and have include all types of pancreas and have shown no clearcut benefit of octreotide after pancreaticoduodenectomy (PD). Soft pancreas and normal sized duct are the risk factors for fistula following PD. This study's focus is on this select group of patients and aims to assess the role of octreotide in patients with soft pancreas.
Study design: Prospective open labeled randomized trial. AIM: Study aims at assessing the influence of octreotide on pancreatic fistula or complications following pancreatoduodenectomy in patients with soft pancreas. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01696903 -
Evaluation of a Novel Pancreaticojejunostomy Technique for Pancreaticoduodenectomy
|
N/A | |
| Recruiting |
NCT05155878 -
Prognostic Factors in Periampullary Tumors and Cysts
|
||
| Terminated |
NCT03757455 -
ERAS Protocol in Pancreaticoduodenectomy and Total Pancreatectomy
|
N/A | |
| Recruiting |
NCT05212350 -
Total pancrEaTectomy vs High-Risk Pancreatic anastomosiS
|
N/A | |
| Completed |
NCT04609137 -
Early Drain Removal Versus Standard Drain Management After Distal Pancreatectomy (Early-Dist)
|
N/A | |
| Recruiting |
NCT04798560 -
Identifing Risk Factors for Pancreaticojejunostomy Leakage Following Pancreaticoduodenectomy
|
||
| Completed |
NCT03627559 -
Early Detection of Anastomotic Leakage by Microdialysis Catheters
|
||
| Completed |
NCT01550406 -
Use of Polyethylene Glycolic Acid or Tachocomb to Prevent Pancreatic Fistula Following Distal Pancreatectomy
|
Phase 4 | |
| Recruiting |
NCT04783831 -
Biodegradable Pancreatic Stents for the Prevention of Postoperative Pancreatic Fistula After Cephalic Pancreaticoduodenectomy
|
||
| Not yet recruiting |
NCT05387538 -
One-layer Versus Two-layer Duct-to-mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy .
|
N/A | |
| Active, not recruiting |
NCT02775227 -
HYPAR Trial - Hydrocortisone vs. Pasireotide in Reducing Pancreatic Surgery Complications
|
Phase 4 | |
| Completed |
NCT02790333 -
Different Stapler Cartridge For Pancreatic Stump Texture To Prevent Pancreatic Fistula
|
N/A | |
| Not yet recruiting |
NCT05657366 -
Peritoneal Lavage on the Incidence of Pancreatic Fistula and Related Complications After Pancreatoduodenectomy
|
N/A | |
| Completed |
NCT03419676 -
Use of Hemopatch as a Sealant at the Pancreaticojejunostomy After Pancreatoduodenectomy
|
Phase 3 | |
| Recruiting |
NCT05297136 -
Preoperative Endoscopic Pancreatic Stent for Distal Pancreatectomy
|
N/A | |
| Completed |
NCT00679952 -
Closed Suction Drainage and Natural Drainage of the Pancreatic Duct in Pancreaticojejunostomy
|
Phase 3 | |
| Completed |
NCT00931554 -
Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections
|
N/A | |
| Recruiting |
NCT04380506 -
Validations of New cut-of for the Stratification of Postoperative Complications,Drains Management
|
N/A | |
| Recruiting |
NCT06283160 -
Metabolomic and Immune Profiling in the Development of Pancreatic Fistulas After Cephalic Duodenopancreatectomy
|
||
| Completed |
NCT02784990 -
Study of Pancreatic Enzymes in the Drains as Early Biomarkers of Post-operative Pancreatic Fistula and Its Clinical Repercussions
|