Pancreatic Ductal Adenocarcinoma Clinical Trial
— CEBOIDSOfficial title:
Celiac Plexus Block to Reduce Opioid Consumption Following Hepato-pancreato-biliary Mini-invasive Surgery: a Randomized Controlled Trial
The goal of this study is to assess the efficacy of intraoperative celiac plexus block (CPB) to reduce opioid consumption following laparoscopic hepato-pancreato-biliary surgery
Status | Not yet recruiting |
Enrollment | 60 |
Est. completion date | December 31, 2025 |
Est. primary completion date | August 31, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Over age 18 - Undergoing laparoscopic hepato-pancreato-biliary surgery Exclusion Criteria: - Patient refuse - Relatively contraindications: severe heart, liver, or kidney dysfunction, coagulation dysfunction, and local anesthetic allergy history - Intervention unlikely to be effective: drug abuse history, receiving other types of nerve block treatment - Unlikely to complete the follow-up: alcoholism, planned to replace WeChat and phone within three months; the expected life span less than three months - Unable to cooperate with the questionnaire and use the patient-controlled analgesia pump |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Sixth Affiliated Hospital, Sun Yat-sen University |
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Teo ZHT, Tey BLJ, Foo CW, Wong WY, Low JK. Intraoperative Celiac Plexus Block With Preperitoneal Infusion Reduces Opioid Usage in Major Hepato-pancreato-biliary Surgery: A Pilot Study. Ann Surg. 2021 Jul 1;274(1):e97-e99. doi: 10.1097/SLA.0000000000004883. — View Citation
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* Note: There are 22 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Postoperative opioid use | The primary outcome will be morphine equivalent during the first postoperative 24 h | Up to 24 h after surgery | |
Secondary | Postoperative opioid use | Patients will be recorded for up to 72 h postoperative opioid consumption. | Up to 72 h after surgery | |
Secondary | Numeric rating scale (NRS) for pain | Patients will be asked to complete a daily diary up to 72 h that records numeric pain rating scale | Up to 72 h after surgery | |
Secondary | Postoperative vomiting | Incidence of postoeprative vomiting will be recorded for up to 72 h | Up to 72 h after surgery | |
Secondary | Quality of recovery using the 15-item quality of recovery questionnaire (QoR-15) | Patients will be asked to complete a 15-item quality of recovery questionnaire up to 72 h after surgery | Up to 72 h after surgery | |
Secondary | Post-anesthesia care unit (PACU) time | Length of PACU stay | Through study completion, an average of 1 year | |
Secondary | Post-operative hospital time | Length of hospital stay | Through study completion, an average of 1 year |
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