Pancreatic Ductal Adenocarcinoma Clinical Trial
Official title:
Impatto Della Revisione Radiologica Con Valutazione Multidisciplinare Nella Gestione Terapeutica Dei Pazienti Affetti da Adenocarcinoma Pancreatico (PAC)
The investigators compared two different time periods respectively before and after the application of a dedicated diagnostic and therapeutic protocol for pancreatic ductal adenocarcinoma including multidisciplinary discussion and radiological review of cases, in order to evaluate the impact of the new protocol on surgical failures and overall survival.
Since 2012 in Reggio Emilia a new diagnostic and therapeutic protocol has been implemented
including multidisciplinary team discussion of non-metastatic PDACs and radiological review
of CT scans by an experienced radiologist.
The aim of this study is to measure the impact of this new protocol on the occurrence of
surgical failures, including incomplete resection or surgery in which resection resulted
impossible at all. The investigators also describe the changes in overall survival and
process indicators such as the proportion of patients referred to different therapeutic
options (upfront surgery, neoadjuvant chemotherapy and no surgery) and the compliance with
referral.
Through a population-based cohort study, the investigators evaluated the impact of the new
protocol on therapeutic management and surgical outcome of patients with non-metastatic PDAC
by comparing two four-years periods, respectively 2008-2011 and 2013-2016, before and after
the introduction of the protocol. Since 2012 was the transitional year when the protocol was
introduced, patients diagnosed with PDAC in 2012 were excluded.
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