Clinical Trials Logo
  1. Home
  2. Pancreatic Cyst
  3. NCT05568433

New Biomarkers in the Intracystic Liquid of Inflammatory and Non-inflammatory Pancreatic Cysts

Pancreatic Cyst Clinical Trial

Official title:
New Biomarkers in the Intracystic Liquid of Cystic Pancreatic Lesions

Clinical Trial Summary

Due to the advances made in the field of the imaging techniques and their common use, pancreatic cysts are more and more incidentally found. Pancreatic pseudocysts can be misdiagnosed as cystic neoplasms, in particular when there is no clinical history of acute or chronic pancreatitis. Pancreatic cystic neoplasms on the other hand are rare, but are difficult to diagnose accurately. Neutrophil gelatinase-associated lipocalin (NGAL) , interleukin 1 Beta (IL1beta) and High Mobility Group AT-Hook 2 (HmgA2) are molecules implicated in the process of inflammation and tumour development. The diagnostic value of their concentration in pancreatic cysts is not established yet. Study aim to asses the significance of NGAL,IL1Beta and HMGA2 concentration in cystic fluid obtained by endoscopic ultrasound (EUS) with EUS-guided fine-needle aspiration (EUS-FNA) and serum level for discriminating between inflammatory and non-inflammatory pancreatic cyst.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05568433
Study type Observational
Source Iuliu Hatieganu University of Medicine and Pharmacy
Contact
Status Completed
Phase
Start date April 2, 2018
Completion date November 30, 2020
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05572788 - Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts N/A
Completed NCT01770405 - Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract N/A
Completed NCT01643460 - Endoscopic Ultrasound (EUS)-Guided Ablation of Pancreatic Cysts N/A
Recruiting NCT03260842 - Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer
Recruiting NCT04291651 - UCSF PANC Cyst Registry
Recruiting NCT05692596 - The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
Recruiting NCT03334708 - A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
Recruiting NCT04140435 - EUS-guided Through-the-needle Microforceps Biopsy Outcomes
Terminated NCT00550108 - Management of Incidentally Discovered Pancreatic Cysts Phase 3
Recruiting NCT03492151 - Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions
Completed NCT03169842 - Cyst Fluid Glucose for On-site Diagnosis of Mucinous Pancreatic Cysts N/A
Not yet recruiting NCT06320990 - Chemoprevention With Tamoxifen in Pre-Invasive Pancreas Mucinous Cystic Neoplasms Not Undergoing Immediate Resection Phase 1
Recruiting NCT04404101 - Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies N/A
Recruiting NCT06305728 - A Study of Early Cancer Detection in People at High Risk of Developing Pancreatic Ductal Adenocarcinoma (PDAC)
Recruiting NCT06340620 - EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope N/A
Recruiting NCT02343692 - A Phase II Multicentre Trial of Endoscopic Ultrasound Guided Radiofrequency Ablation of Cystic Tumours of the Pancreas N/A
Recruiting NCT02775461 - Pancreas Registry and High Risk Registry
Active, not recruiting NCT01563133 - Clinical Evaluation Of Needle-based Confocal Laser Endomicroscopy in The Lymph Nodes Along With Masses and Cystic Tumors of the Pancreas N/A
Completed NCT00222898 - Cancer Detection in Pancreatic Cysts N/A
Not yet recruiting NCT06276764 - The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)