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Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors — PAVO  

Pancreatic Cancer Clinical Trial

Official title:
A Single-Arm Phase-II Study of Niraparib in Locally Advanced or Metastatic Solid Tumor Patients With PALB2 Mutations

Clinical Trial Summary

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors and a pathogenic or likely pathogenic tumor PALB2 (tPALB2) mutation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Breast Neoplasms
  • Breast Tumor
  • Colonic Neoplasms
  • Endometrial Cancer
  • Endometrial Neoplasms
  • Esophageal Cancer
  • Esophageal Neoplasms
  • Head and Neck Cancer
  • Head and Neck Neoplasms
  • Locally Advanced Solid Tumor
  • Lung Neoplasms
  • Lung Tumor
  • Melanoma
  • Metastatic Cancer
  • Neoplasm Metastasis
  • Neoplasms
  • Pancreatic Cancer
  • Pancreatic Neoplasms
  • Solid Tumor
  • Urologic Cancer
  • Urologic Neoplasms
Clinical Trial Details
NCT number NCT05169437
Study type Interventional
Source Tempus AI
Contact
Status Active, not recruiting
Phase Phase 2
Start date March 15, 2022
Completion date January 1, 2025
View Details
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