Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients

Clinical Trial Summary

Given the efficacy of nanoliposomal irinotecan as a second-line regimen in pancreatic ductal adenocarcinoma (PDAC), together with the favorable toxicity profile of paricalcitol and its interplay with irinotecan metabolism, the investigators propose a second-line pilot study in advanced PDAC that will enroll patients who have progressed on a gemcitabine-based regimen.

See also
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NCT number	NCT03883919
Study type	Interventional
Source	Washington University School of Medicine
Contact
Status	Completed
Phase	Phase 1
Start date	July 11, 2019
Completion date	July 2, 2022

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms