Pancreatic Cancer Clinical Trial
Official title:
Functional Magnetic Resonance Imaging of Pancreatic Cancer: a Feasibility and Reproducibility Study
Novel predictive markers are needed to determine treatment efficacy in pancreatic cancer at an early stage. Preferably, these markers could be determined non-invasively and provide insight into the biology of pancreatic cancer. Several MR techniques can serve for this purpose. However, optimalisation of these techniques is needed and their reproducibility should be assessed.
Background of the study:
Novel predictive markers are needed to determine treatment efficacy in pancreatic cancer at
an early stage. Preferably, these markers could be determined non-invasively and provide
insight into the biology of pancreatic cancer. Several MR techniques can serve for this
purpose. However, optimalisation of these techniques is needed and their reproducibility
should be assessed.
Objective of the study:
To optimize DCE-MRI, T2* MRI and DWI in pancreatic cancer at 3T and investigate its
reproducibility.
Study design:
In the first part of the study, patients with pancreatic cancer will undergo an MR
measurement protocol once at 3T, to optimize MR techniques (DCE-MRI, T2* MRI and DWI). In
the second part of the study, to assess reproducibility patients will undergo the MR
measurement protocol twice within one week before start of any treatment.
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