Pancreatic Cancer Clinical Trial
Official title:
A Pilot Study of Full Dose Gemcitabine and Hypofractionated Stereotactic Radiosurgery in the Treatment of Unresectable Pancreatic Cancer
People with pancreatic cancer that cannot be cured by surgery are being asked to participate
in this study.
The purpose of this study is to test the ability of the radiation oncologists to administer
Cyberknife therapy along with Gemcitabine chemotherapy for patients with pancreatic cancer.
Radiation and Gemcitabine are both effective at killing cancer cells but they generally
cannot be given at the same time. Cyberknife therapy is highly focused radiation that is
being used extensively at Georgetown University and around the United States to treat a
number of cancers. It is believed that because Cyberknife is so highly focused it can be
given safely with regular doses of chemotherapy to attack cancer cells in two ways at the
same time.
This research is being done because it is not known if using Cyberknife with chemotherapy
will be a safe way to treat pancreatic cancer.
This is a single arm, open-label pilot study of Cyberknife plus Gemcitabine in 10 patients with locally advanced pancreatic cancer who have not received prior local or systemic therapy for their pancreatic cancer. ;
Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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