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Opioid Sparing Effect of Thoracic Epidural Analgesia for Open Upper Abdominal Surgery

Pancreas Cancer Clinical Trial

Official title:
Opioid Sparing Effect of Thoracic Epidural Analgesia for Open Upper Abdominal Surgery: Prospective Randomized Controlled Trial

Clinical Trial Summary

This prospective randomized controlled study is aimed to determine the advantages of thoracic epidural analgesia for open upper abdominal surgery in combination with multimodal analgesia compared with no thoracic epidural analgesia on postoperative pain control. The primary outcome is total opioid consumption in postoperative 72 hours. Secondary outcomes are the success of continuous epidural analgesia or complications of this technique, pain intensity, morbidity and mortality compare to no continuous epidural analgesia.

Clinical Trial Description

Continuous epidural analgesia (CEA) for open upper abdominal surgery has been showed the analgesic analgesia for open abdominal surgery. However the technical difficulty, complications especially hypotension, pruritus of CEA impede the popularity of technique compared to intravenous patient-controlled analgesia (IV PCA) in multimodal analgesia. This study is aimed to study of the role of CEA and multimodal analgesia in open abdominal surgery compare to IV PCA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04920019
Study type Interventional
Source Mahidol University
Contact
Status Completed
Phase N/A
Start date October 22, 2020
Completion date August 20, 2023
View Details
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