Pancreas Cancer Clinical Trial
Official title:
Preoperative Systemic Inflammatory Biomarkers and Postoperative Day 1 Drain Amylase Value Predict Grade C Pancreatic Fistula After Pancreaticoduodenectomy: a Retrospective Single Center Experience
Verified date | April 2020 |
Source | Campus Bio-Medico University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Particularly, pancreatic fistula is the most common and serious complication after pancreaticoduodenectomy (PD) and is reported in up to 40% of cases. The aim of this retrospective single-center study was to investigate the utility of the combination of preoperative inflammation biomarkers (PIBs) with postoperative day 1 drains amylase (POD1-d.a.) levels in predicting grade C Pancreatic Fistula (PF).
Status | Completed |
Enrollment | 227 |
Est. completion date | April 1, 2020 |
Est. primary completion date | December 31, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Patients underwent pancreaticoduodenectomy (PD) for periampullary neoplasms - Patients underwent PD with pancreaticojejunostomy reconstruction. - Patient with data of blood count in first postoperative day Exclusion Criteria: - None of the above criteria |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Campus Bio-Medico University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Predictive value of PIBs and drains amylase values for Pancreatic Fistula (PF) | Predictive Values (PPV) and Negative Predictive Values (NPV) were computed to investigate the probability to develop Pancreatic Fistula (PF) combining PIBs and Postoperative Day 1 Drain Amylase Value | pre-intervention/ Day 1 after the intervention/up to discharge" |
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