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Clinical Trial Summary

We are going to establish "organoid" models from pancreatic cancer biopsies achieved via EUS-FNA. Then the sensitivity of the selected FDA-approved anti-cancer drugs will be tested in these organoids.


Clinical Trial Description

The survival rate of pancreatic cancer, a kind of malignant tumor, remains poor due to lack of effective treatments. Recently, a new model called "organoid" has been generated from human and murine pancreatic cancer tissues. These organoids are developed from large pieces of surgical tissues or small biopsies taken from EUS-FNA guided samples. Here in our study we are going to establish "organoid" models from pancreatic cancer biopsies achieved via EUS-FNA. After successful generation of these organoids, we will treat them with the selected FDA-approved anti-cancer drugs, and assess the responses to these anti-cancer agents in our established organoids. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03544255
Study type Observational
Source The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Contact Shu Zhang, PhD
Phone +86 13770728926
Email zhangshu19900513@126.com
Status Recruiting
Phase
Start date May 1, 2018
Completion date June 1, 2021

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