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Clinical Trial Summary

The purpose of this study is to investigate responses of pain and the maintenance of mechanical muscle hypersensitivity following an acute exercise-induced ischemic condition repeated over time in a prolonged NGF-sensitized muscle. Additionally, the influence of the pain modulating system on prolonged NGF muscle hypersensitivity caused by peripheral mechanisms and central mechanisms will also be investigated.


Clinical Trial Description

The hypothesis is that an ischemic conditioning in a NGF-sensitized muscle is able to facilitate pain responses and that over time the pain modulation system is responsible for a subsequent reduction in muscle sensitivity towards mechanical pressure and a decrease in pain intensity following a period of NGF-induced muscle hypersensitivity. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03844243
Study type Interventional
Source Aalborg University
Contact Line Bay Sørensen, PhD. stud.
Phone 52373229
Email lbs@hst.aau.dk
Status Recruiting
Phase Early Phase 1
Start date February 18, 2019
Completion date June 30, 2019

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