Pain Relief Clinical Trial
Official title:
Efficacy and Adverse Events of Morphine and Fentanyl in an Aeromedical Setting
NCT number | NCT00580489 |
Other study ID # | IRB06-00065 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | August 2006 |
Est. completion date | December 2008 |
Verified date | July 2022 |
Source | MetroHealth Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The study is exempt from informed consent by the MetroHealth Medical Center institutional review board (IRB), because two standards of care are used and there is no increased clinical risk to the patient due to the study. The researchers randomize either fentanyl or morphine to be given to trauma patients and record how their pain scale is treated along with observing for adverse events. They are looking to see if the hypothesized benefits of fentanyl (which is much more expensive than morphine) actually exist.
Status | Completed |
Enrollment | 204 |
Est. completion date | December 2008 |
Est. primary completion date | December 2008 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 69 Years |
Eligibility | Inclusion Criteria: - Trauma patient - Able to speak/communicate a pain scale Exclusion Criteria: - Age <18 - Age >69 - Initially or any time hypotensive - Prisoner |
Country | Name | City | State |
---|---|---|---|
United States | MetroHealth Medical Center | Cleveland | Ohio |
Lead Sponsor | Collaborator |
---|---|
MetroHealth Medical Center |
United States,
Smith MD, Wang Y, Cudnik M, Smith DA, Pakiela J, Emerman CL. The effectiveness and adverse events of morphine versus fentanyl on a physician-staffed helicopter. J Emerg Med. 2012 Jul;43(1):69-75. doi: 10.1016/j.jemermed.2011.05.018. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mean Change in Numeric Pain Score (NPS) From First to Last Dose | Mean difference in the numeric pain score (NPS) from the first dose to the final dose of medication administered.
A significant mean pain score change is defined as greater than or equal to 2 Numeric Pain Score (NPS) 0-10, 0 Least pain, 10 most pain |
Medication was administered over a mean transport time of 37 minutes in the Morphine group and 43 minutes in the Fentanyl group. | |
Secondary | Recording of Instance of Narcotic Side Effects. | Instances of narcotic side effects (vital sign derangement, itching, nausea/vomiting) . | Groups were observed a mean of 37 minutes in the Morphine Group and a mean of 43 minutes in the Fentanyl group for side effects. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02901561 -
Comparison Between 2 Doses of Misoprostol Before Intrauterine Device
|
Phase 2/Phase 3 | |
Completed |
NCT02905058 -
Efficacy of Ketoprofen Before Intrauterine Device Insertion
|
Phase 3 | |
Completed |
NCT02905045 -
Efficacy of Ketoprofen Before Hysterosalpingography
|
Phase 3 | |
Recruiting |
NCT00773760 -
MOR and COMT SNP Polymorphism and Pain
|
N/A | |
Completed |
NCT03733015 -
Daily Sessions of rTMS to the Left DLPFC Modulate the Pain Thresholds and CPM
|
N/A | |
Completed |
NCT02943135 -
Lidocaine In-situ Gel Before Intrauterine Device Insertion
|
Phase 3 | |
Completed |
NCT04473508 -
Erectus Nerve Block for Lumbar Spine Surgery
|
Phase 3 | |
Completed |
NCT02969902 -
Buzzy Distraction During Venipuncture
|
N/A | |
Enrolling by invitation |
NCT03184649 -
Ibuprofen, Paracetamol Versus Placebo on Pain During Local Anesthetic Injection (RCT)
|
Phase 1/Phase 2 | |
Completed |
NCT02614391 -
Tablet Distraction for Pain Control During Venipuncture
|
Phase 3 | |
Recruiting |
NCT00768014 -
fMRI Measurements on Pain Relief Methods in First Stage Labor Pain
|
N/A | |
Completed |
NCT04586712 -
Efficacy of a Controlled Short-term Trial of Cannabidiol (CBD) Ingestion on Reducing Symptomatic Response and Facilitating Recovery After Induced Muscle Injury
|
Phase 2 | |
Not yet recruiting |
NCT04781777 -
Effect of Ultrasonographic Guided Insulin Injection With Dexamethasone and Local Anesthetic Mixture in Diabetic Patients With Mild to Moderate Carpal Tunnel .
|
N/A | |
Recruiting |
NCT06456177 -
Nociception Monitoring During Epidural Analgesia
|
||
Recruiting |
NCT00914498 -
The Effect of Pre-incisional Local Xylocaine Injection on Post Operative Pain and Scar Formation After Cesarean Section
|
N/A | |
Completed |
NCT00638274 -
Comparison of Loss of Resistance Techniques
|
Phase 2 | |
Recruiting |
NCT04656821 -
Erector Spinae Block Versus Thoracic Paravertebral Block for Acute Thoracic Herpes Zoster
|
Phase 4 | |
Withdrawn |
NCT01263652 -
Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients
|
N/A | |
Completed |
NCT01925469 -
Benzocaine Versus Placebo Spray for Pain Relief at Hysterosalpingogram
|
Phase 4 | |
Completed |
NCT03263884 -
Repetitive Transcranial Magnetic Stimulation and the Development of Ongoing Muscle Pain
|
N/A |