Pain Measurement Clinical Trial
Official title:
Comparison Between Dexamethasone and Ibuprofen on Postoperative Pain Prevention and Control Following Surgical Implant Placement: a Double-Blind, Parallel-Group, Placebo-Controlled Randomized Clinical Trial
Background and aim: Postoperative pain is an adverse effect of oral surgeries and may
therefore be prevented or minimized. This study compares the efficacy of preemptive
ibuprofen and dexamethasone protocols in pain prevention and control after surgical implant
placement.
Methods: For this prospective, double-masked, parallel-group, placebo-controlled, randomized
clinical trial, 117 dental implants were placed. The groups received three different
protocols 1 hour before surgery:
1. 600 mg ibuprofen (and another 600 mg dose 6 hours after the first dose);
2. 4 mg dexamethasone (and another 4 mg 6 hours after the first dose) or
3. placebo.
Rescue medication (1000 mg acetaminophen) was given to each patient who was instructed to
take it if necessary. Pain intensity was evaluated by a 101-point numeric rate scale and
visual analogue scale, additionally discomfort was evaluated using a four-point verbal rate
scale, hourly for the first 8 hours after surgery and three times a day on the following 3
days.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00524927 -
Safety and Efficacy of Methoxyflurane for Treatment of Incident Pain
|
Phase 4 | |
| Completed |
NCT04557982 -
Creating a Czech Version of the Simplified Faces Pain Scale and the Simplified Concrete Ordinal Pain Scale
|
||
| Completed |
NCT04124289 -
A Functional Pain Scale to Improve the Patient Experience
|
||
| Completed |
NCT03675945 -
Smartphone Evaluation of Postoperative Pain Profiles Following General Surgery in Children
|
||
| Active, not recruiting |
NCT04451252 -
Predicting Response to Interventional Pain Management Techniques in Chronic Low Back Pain in a Prospective Cohort.
|
||
| Completed |
NCT03727373 -
Qualitative Study for Pain Measurement Using Innovative Health Technology
|
||
| Not yet recruiting |
NCT04555928 -
Measuring Pain Intensity in Older Patients: A Comparison of Five Scales
|
||
| Recruiting |
NCT06201195 -
Anterior Cutaneus Nerve Block With USG for Total Knee Replacement
|
N/A | |
| Completed |
NCT02603783 -
Esophageal capsaïcin Infusion and Mucosal Integrity
|
N/A | |
| Completed |
NCT04050384 -
Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates
|
N/A | |
| Recruiting |
NCT05129007 -
Pain Monitoring of Herniated Disc Surgery Patients With Oura Ring
|
||
| Completed |
NCT05881551 -
Pain Assessment Via Force Measurement Using eEgg After Blockade of the Lumbar Facet Joints
|
N/A | |
| Completed |
NCT04888026 -
Impact on Pain Sensitivity of Clinical Interaction
|
N/A | |
| Recruiting |
NCT05223790 -
Assessment of the NIPE in Very Premature Infant Ventilated and Sedated in Neonatal Reanimation.
|
||
| Terminated |
NCT02630134 -
Device for Monitoring Pain During Intraoperative, Pre/Post Surgical Periods: Comparison With Standard of Care Monitoring
|
N/A | |
| Completed |
NCT05822336 -
Duration of IM Injection and Pain Intensity
|
N/A | |
| Completed |
NCT02919891 -
Relationship of Intra-Epidermal Nerve Fibre Density (IENFD) and Structure to Chronic Post-Mastectomy Pain Syndrome (PMPS)
|
||
| Completed |
NCT04392180 -
COA-APTIC Caregiver Concept Elicitation Study
|
||
| Completed |
NCT01211600 -
Cesarean Trial of Staples vs. Sutures
|
N/A | |
| Completed |
NCT02769598 -
Pain Management in Pediatric Intensive Care by Studying the Autonomic Balance
|
N/A |