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Pachychoroid Disease clinical trials

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NCT ID: NCT06466018 Recruiting - Ocular Rosacea Clinical Trials

Research Into Diagnostic and Prognostic Molecular and Imaging Biomarkers of Ocular Disorders Associated With Neurovascular Deregulation: Biocor Cohort

BIOCOR
Start date: March 19, 2024
Phase: N/A
Study type: Interventional

BIOCOR is an interventional clinical trial whose main objectives are Objectif are identify molecular biomarker(s) of ocular rosacea and pachychoroid. Endpoints are : Correlation between pachychoroidosis (defined by choroidal phenotype parameters in OCT and autofluorescence) or the stage of ocular rosacea (ROSCO(29) definition) and biological markers selected on the basis of preclinical work (animal model) and by unbiased methods (proteomics, metabolomics, meibum lipidomics). The study of circulating, ocular and functional biomarkers would enable us to confirm our hypothesis and identify patients who could benefit from treatments that regulate the ANS and/or mineralocorticoid pathways.

NCT ID: NCT04498000 Completed - Clinical trials for Pachychoroid Disease

Analysis of the Pachychoroid Phenotype in an Asian Population

Start date: July 22, 2020
Phase:
Study type: Observational [Patient Registry]

The understanding of pachychoroid phenotype is incomplete. It is important to understand the risk of conversion from an uncomplicated pachychoroid phenotype to the pachychoroid disease phenotype, to guide appropriate management of these patients.