A Major Determinant Focused on the ECG or Echocardiogram for PICM and Its Clinical Outcome (PICM Syndrome)

Pacemaker Complication Clinical Trial

Official title: A Major Determinant Focused on the ECG or Echocardiogram for Pacing-induced Cardiomyopathy (PICM) and Its Clinical Outcome (PICM Syndrome) : Prospective, Multi-center, Observational Cohort Study.

Status Recruiting

Clinical Trial Summary

Chronic right ventricular pacing has a deleterious effect on left ventricular (LV) function, namely pacing-induced cardiomyopathy (PICM). Several parametes make difference of effect on the occurrence of PICM and its subsequent clinical outcomes. In particular, recognition of a major determinant focused on the ECG or echocardiographic parameters including strain or genetic factor for occurrence of PICM may lead to better identification of patients at high risk. Investigators prospectively enroll a participant with documented high risk of PICM and clinically follow-up to idenify clinical impact of PICM (PICM syndrome) over a long period of time.

Clinical Trial Description

Investigators investigate a major determinant focused on the ECG or echocardiogram or genetic factor to predict the PICM after implantation of pacemaker. Not only QRS duration and mechanical strain but also genetic factor could be also investigated to predict the occurrence of PICM before diagnosis fo PICM ;

Related Conditions & MeSH terms

• Pacemaker Complication

• NCT number: NCT03475498
• Study type: Observational [Patient Registry]
• Source: Eulji University Hospital
• Contact: Ki-Woon Kang, MD., PhD.
• Phone: 81 10 4492 2136
• Email: kwkang0115@gmail.com
• Status: Recruiting
• Start date: March 1, 2018
• Completion date: February 28, 2028