Overdose Clinical Trial
Official title:
Assessing the Impact of Overdose Prevention Centers as a Polysubstance Use and Behavioral Health Intervention in New York City
The aims of this study are: (Aim 1) Identify sources of heterogeneous impacts of opioid prevention center (OPC) use on non-fatal and fatal overdose risk among individuals with histories of polysubstance use (PSU); (Aim 2) Estimate the impact of OPC use on treated psychiatric events among clients with histories of PSU, and; (Aim 3) Assess the barriers and facilitators of integrating mental health services into existing syringe service and OPC delivery models.
Status | Not yet recruiting |
Enrollment | 500 |
Est. completion date | September 30, 2026 |
Est. primary completion date | December 31, 2024 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: Aims 1 and 2: - are 18 years of age or older; - engaged in syringe service program and/or overdose prevention center services in New York City in the past 30 days before the date of enrollment; - are able to complete assessments in English or Spanish; - are competent to give written informed consent at the time of the interview; - are able to provide informed consent; - self-report use of illicit opioids (e.g., heroin, fentanyl), illicit stimulants (e.g., powder cocaine, crack, methamphetamine), counterfeit prescription pills (defined as prescription pills obtained through the illicit drug market) or any injection drug use in the past 30 days, and - are able to participate for at least 6 months following enrollment. Aim 3 - are 18 years of age or older; - are employed by a harm reduction program; - are able to complete assessments in English; and - are able to provide informed consent. Exclusion Criteria: • Individuals not meeting the criteria detailed above for the respective Aims will not be eligible for participation in this study. |
Country | Name | City | State |
---|---|---|---|
United States | NYU Langone Health | New York | New York |
Lead Sponsor | Collaborator |
---|---|
NYU Langone Health | Centers for Disease Control and Prevention |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Incidence of Fatal Overdose | Incidence of fatal overdose will be derived from overdose mortality data from the NYC Office of the Chief Medical Examiner. | Up to Month 12 | |
Primary | Incidence of Non-Fatal Overdose | Incidence of nonfatal overdose will be assessed using hospitalization and emergency department data from the NYC Regional Health Information Exchange (RHIO) and Statewide Research and Planning Cooperative System (SPARCS). | Up to Month 12 | |
Primary | Incidence of Psychiatric Services Utilization | Psychiatric services utilization will be assessed from SPARCS, RHIO, and NYS Medicaid. | Up to Month 12 |
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