Overactive Bladder Clinical Trial
Official title:
Gene Expression in the Bladder in Children With an Overactive Bladder and Daytime Urinary Incontinence
The aim of this study (the hypothesis) is to identify differences in the gene expression
profile in the bladder muscle and hereby gain greater knowledge about the muscular
mechanisms that cause overactive bladder and daytime urinary incontinence in children older
than 5 years. A secondary aim is to examine how this gene expression profile differs from
children with a neurogenic overactive bladder and how the gene expression profile changes
from childhood till adulthood. Such new knowledge will result in a more precisely targeted
and hence effective treatment of overactive bladder.
The results will be obtained by retrieving bladder biopsies from children and adults
suffering from an overactive bladder or a neurogenic bladder. These biopsies will undergo
molecular analysis and the investigators will compare them with biopises from bladder
healthy adults and children.
n/a
Time Perspective: Prospective
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